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Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection.
Fresenius J Anal Chem. 2000 Jun; 367(4):359-63.FJ

Abstract

Nonaqueous capillary electrophoresis (NACE) was applied to the determination of illicit drugs. The complete separation of amphetamine, methamphetamine, 3,4-methylene dioxy amphetamine (MDA), 3,4-methylene dioxy methamphetamine (MDMA), mescaline, cocaine and benzoylecgonine was obtained using an acetonitrile based buffer solution containing 10 mM sodium acetate and 1 M acetic acid. Electrochemical detection using a Pt microdisk electrode set to a potential of +1.8 V was found to be selective for MDA, MDMA and mescaline. The detection limits for these compounds were in the low ng/mL range which is between 2 and 3 orders of magnitude lower compared to UV-detection.

Authors+Show Affiliations

University of Kansas, Department of Chemistry, Lawrence 66045, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11225861

Citation

Backofen, U, et al. "Analysis of Illicit Drugs By Nonaqueous Capillary Electrophoresis and Electrochemical Detection." Fresenius' Journal of Analytical Chemistry, vol. 367, no. 4, 2000, pp. 359-63.
Backofen U, Matysik FM, Hoffmann W, et al. Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection. Fresenius J Anal Chem. 2000;367(4):359-63.
Backofen, U., Matysik, F. M., Hoffmann, W., & Lunte, C. E. (2000). Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection. Fresenius' Journal of Analytical Chemistry, 367(4), 359-63.
Backofen U, et al. Analysis of Illicit Drugs By Nonaqueous Capillary Electrophoresis and Electrochemical Detection. Fresenius J Anal Chem. 2000;367(4):359-63. PubMed PMID: 11225861.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection. AU - Backofen,U, AU - Matysik,F M, AU - Hoffmann,W, AU - Lunte,C E, PY - 2001/2/28/pubmed PY - 2001/3/17/medline PY - 2001/2/28/entrez SP - 359 EP - 63 JF - Fresenius' journal of analytical chemistry JO - Fresenius J Anal Chem VL - 367 IS - 4 N2 - Nonaqueous capillary electrophoresis (NACE) was applied to the determination of illicit drugs. The complete separation of amphetamine, methamphetamine, 3,4-methylene dioxy amphetamine (MDA), 3,4-methylene dioxy methamphetamine (MDMA), mescaline, cocaine and benzoylecgonine was obtained using an acetonitrile based buffer solution containing 10 mM sodium acetate and 1 M acetic acid. Electrochemical detection using a Pt microdisk electrode set to a potential of +1.8 V was found to be selective for MDA, MDMA and mescaline. The detection limits for these compounds were in the low ng/mL range which is between 2 and 3 orders of magnitude lower compared to UV-detection. SN - 0937-0633 UR - https://www.unboundmedicine.com/medline/citation/11225861/Analysis_of_illicit_drugs_by_nonaqueous_capillary_electrophoresis_and_electrochemical_detection_ L2 - https://dx.doi.org/10.1007/s002160000371 DB - PRIME DP - Unbound Medicine ER -