Tags

Type your tag names separated by a space and hit enter

A study of gastric emptying in chronic renal failure.
J Assoc Physicians India. 1997 Nov; 45(11):835-8.JA

Abstract

In a prospective controlled study, 32 patient with chronic renal failure (CRF) and 11 healthy volunteers were evaluated for solid gastric emptying at our institute over a period of 2 years. The study sought to identify the incidence of abnormal gastric emptying in these patients, the factors influencing the development of abnormal gastric emptying and whether gastrointestinal symptoms correlated with abnormal gastric emptying. The efficacy of prokinetic drugs Cisapride and Erythromycin in improving delayed gastric emptying in these patients with CRF was also compared and evaluated. We observed delayed gastric emptying in 69% of our patients. About 50% of our patients with delayed gastric emptying had no gastrointestinal symptoms suggesting a poor correlation between the two. Delayed gastric emptying was observed frequently in patients with peripheral neuropathy and/or autonomic neuropathy. Gastric emptying in CRF appears to be independent of age, sex, duration of disease, BUN, creatinine and H. phylori infection. Oral Cisapride and Erythromcin are effective gastrokinetic agents in these patients. Identification of delayed gastric emptying in patients with CRF and treatment with these drugs may reduce gastrointestinal symptom related morbidity.

Authors+Show Affiliations

Dept of General Medicine, TNM College and BYL Nair Charitable Hospital, Mumbai.No affiliation info available

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

11229179

Citation

Alimchandani, A, and J V. Pai-dhungat. "A Study of Gastric Emptying in Chronic Renal Failure." The Journal of the Association of Physicians of India, vol. 45, no. 11, 1997, pp. 835-8.
Alimchandani A, Pai-dhungat JV. A study of gastric emptying in chronic renal failure. J Assoc Physicians India. 1997;45(11):835-8.
Alimchandani, A., & Pai-dhungat, J. V. (1997). A study of gastric emptying in chronic renal failure. The Journal of the Association of Physicians of India, 45(11), 835-8.
Alimchandani A, Pai-dhungat JV. A Study of Gastric Emptying in Chronic Renal Failure. J Assoc Physicians India. 1997;45(11):835-8. PubMed PMID: 11229179.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A study of gastric emptying in chronic renal failure. AU - Alimchandani,A, AU - Pai-dhungat,J V, PY - 2001/3/7/pubmed PY - 2001/3/17/medline PY - 2001/3/7/entrez SP - 835 EP - 8 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 45 IS - 11 N2 - In a prospective controlled study, 32 patient with chronic renal failure (CRF) and 11 healthy volunteers were evaluated for solid gastric emptying at our institute over a period of 2 years. The study sought to identify the incidence of abnormal gastric emptying in these patients, the factors influencing the development of abnormal gastric emptying and whether gastrointestinal symptoms correlated with abnormal gastric emptying. The efficacy of prokinetic drugs Cisapride and Erythromycin in improving delayed gastric emptying in these patients with CRF was also compared and evaluated. We observed delayed gastric emptying in 69% of our patients. About 50% of our patients with delayed gastric emptying had no gastrointestinal symptoms suggesting a poor correlation between the two. Delayed gastric emptying was observed frequently in patients with peripheral neuropathy and/or autonomic neuropathy. Gastric emptying in CRF appears to be independent of age, sex, duration of disease, BUN, creatinine and H. phylori infection. Oral Cisapride and Erythromcin are effective gastrokinetic agents in these patients. Identification of delayed gastric emptying in patients with CRF and treatment with these drugs may reduce gastrointestinal symptom related morbidity. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/11229179/A_study_of_gastric_emptying_in_chronic_renal_failure_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -