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[Relations between ankylosing spondyloarthritis and HLA-B27 in various ethnic groups in Russia].
Ter Arkh. 2001; 73(1):27-30.TA

Abstract

AIM

To characterize relationship between prevalence of ankylosing spondylarthritis (ASA) and incidence rate of HLA-B27 in genotypically different ethnic groups of Russia with interpolation of the results to other populations.

MATERIAL AND METHODS

2287 individuals from genotypically different ethnic groups were examined in overall one-stage epidemiological trial.

RESULTS

Prevalence of ASA in ethnic groups ranged from 0.2 to 2.0% while occurrence of HLA0B27--from 15 to 40%. Rate of correlation between the disease prevalence and incidence of B27 was 0.82. The equation for calculation of ASA incidence rate by HLA-B27 incidence was devised: AC(%) = -0.40 + 0.06x.

CONCLUSION

In most world populations prevalence of ASA correlates with population frequency HLA-B27 though in some ethnic groups this correlation is absent. Consequently, ASA is genetically heterogenous.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

rus

PubMed ID

11234135

Citation

Erdes, Sh, et al. "[Relations Between Ankylosing Spondyloarthritis and HLA-B27 in Various Ethnic Groups in Russia]." Terapevticheskii Arkhiv, vol. 73, no. 1, 2001, pp. 27-30.
Erdes Sh, Guseva IA, Benevolenskaia LI. [Relations between ankylosing spondyloarthritis and HLA-B27 in various ethnic groups in Russia]. Ter Arkh. 2001;73(1):27-30.
Erdes, S. h., Guseva, I. A., & Benevolenskaia, L. I. (2001). [Relations between ankylosing spondyloarthritis and HLA-B27 in various ethnic groups in Russia]. Terapevticheskii Arkhiv, 73(1), 27-30.
Erdes Sh, Guseva IA, Benevolenskaia LI. [Relations Between Ankylosing Spondyloarthritis and HLA-B27 in Various Ethnic Groups in Russia]. Ter Arkh. 2001;73(1):27-30. PubMed PMID: 11234135.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Relations between ankylosing spondyloarthritis and HLA-B27 in various ethnic groups in Russia]. AU - Erdes,Sh, AU - Guseva,I A, AU - Benevolenskaia,L I, PY - 2001/3/10/pubmed PY - 2001/4/17/medline PY - 2001/3/10/entrez SP - 27 EP - 30 JF - Terapevticheskii arkhiv JO - Ter Arkh VL - 73 IS - 1 N2 - AIM: To characterize relationship between prevalence of ankylosing spondylarthritis (ASA) and incidence rate of HLA-B27 in genotypically different ethnic groups of Russia with interpolation of the results to other populations. MATERIAL AND METHODS: 2287 individuals from genotypically different ethnic groups were examined in overall one-stage epidemiological trial. RESULTS: Prevalence of ASA in ethnic groups ranged from 0.2 to 2.0% while occurrence of HLA0B27--from 15 to 40%. Rate of correlation between the disease prevalence and incidence of B27 was 0.82. The equation for calculation of ASA incidence rate by HLA-B27 incidence was devised: AC(%) = -0.40 + 0.06x. CONCLUSION: In most world populations prevalence of ASA correlates with population frequency HLA-B27 though in some ethnic groups this correlation is absent. Consequently, ASA is genetically heterogenous. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/11234135/[Relations_between_ankylosing_spondyloarthritis_and_HLA_B27_in_various_ethnic_groups_in_Russia]_ L2 - https://medlineplus.gov/ankylosingspondylitis.html DB - PRIME DP - Unbound Medicine ER -