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Untoward effects associated with practolol administration: oculomucocutaneous syndrome.
Br Med J 1975; 1(5958):595-8BM

Abstract

Keratoconjunctivitis sicca, conjunctival scarring, fibrosis, metaplasia, and shrinkage developed in 27 patients as an adverse reaction to practolol. Rashes, nasal and mucosal ulceration, fibrous or plastic peritonitis, pleurisy, cochlear damage, and secretory otitis media also occurred in some cases. Three patients suffered profound visual loss though most retained good vision. Symptoms and signs improved on withdrawal of the drug, but reduction of tear secretion persisted in most patients.

Authors

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1125623

Citation

Wright, P. "Untoward Effects Associated With Practolol Administration: Oculomucocutaneous Syndrome." British Medical Journal, vol. 1, no. 5958, 1975, pp. 595-8.
Wright P. Untoward effects associated with practolol administration: oculomucocutaneous syndrome. Br Med J. 1975;1(5958):595-8.
Wright, P. (1975). Untoward effects associated with practolol administration: oculomucocutaneous syndrome. British Medical Journal, 1(5958), pp. 595-8.
Wright P. Untoward Effects Associated With Practolol Administration: Oculomucocutaneous Syndrome. Br Med J. 1975 Mar 15;1(5958):595-8. PubMed PMID: 1125623.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Untoward effects associated with practolol administration: oculomucocutaneous syndrome. A1 - Wright,P, PY - 1975/3/15/pubmed PY - 1975/3/15/medline PY - 1975/3/15/entrez SP - 595 EP - 8 JF - British medical journal JO - Br Med J VL - 1 IS - 5958 N2 - Keratoconjunctivitis sicca, conjunctival scarring, fibrosis, metaplasia, and shrinkage developed in 27 patients as an adverse reaction to practolol. Rashes, nasal and mucosal ulceration, fibrous or plastic peritonitis, pleurisy, cochlear damage, and secretory otitis media also occurred in some cases. Three patients suffered profound visual loss though most retained good vision. Symptoms and signs improved on withdrawal of the drug, but reduction of tear secretion persisted in most patients. SN - 0007-1447 UR - https://www.unboundmedicine.com/medline/citation/1125623/Untoward_effects_associated_with_practolol_administration:_oculomucocutaneous_syndrome_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1125623/ DB - PRIME DP - Unbound Medicine ER -