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Occurrence and predictors of retinopathy and visual acuity in Type 2 diabetic patients and control subjects. 10-year follow-up from the diagnosis.
J Diabetes Complications 2001 Jan-Feb; 15(1):24-33JD

Abstract

The evolution of visual acuity and retinopathy and their risk factors in patients with newly diagnosed type 2 diabetes and in control subjects. A 10-year prospective study consisting of a representative group of 133 (70 men, 63 women) newly diagnosed type 2 diabetic patients diagnosed at health centers between 1979 and 1981 and 144 (62 men, 82 women) non-diabetic control subjects recruited from the population register. The frequency of retinopathy was determined by grading of 45 degrees fundus photographs at baseline and after 5 and 10 years. By the 10-year follow-up the diabetic patients had lower visual acuity than the control subjects. The impairment of the visual acuity correlated inversely to HbA(1C) value of the 5-year examination. The frequency of retinopathy in type 2 diabetic patients increased sharply after 5 years and at 10-year 55% of diabetic patients had signs of retinopathy. The frequency of retinopathy in the control subjects was low, but detectable. In the diabetic patients poor glycemic control was the most important predictive factor for the development of retinopathy. In the control subjects blood pressure levels were higher and microalbuminuria more common in those with than in those without retinopathy. The visual acuity deteriorated and the frequency of retinopathy increased in newly diagnosed type 2 diabetic patients with duration of disease and poor glycemic control. Interestingly, higher blood pressure levels and microalbuminuria predicted retinopathy in control subjects.

Authors+Show Affiliations

Department of Ophthalmology, Kuopio University Hospital, P.O. Box 1777, FIN 70211 Kuopio, Finland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11259923

Citation

Voutilainen-Kaunisto, R M., et al. "Occurrence and Predictors of Retinopathy and Visual Acuity in Type 2 Diabetic Patients and Control Subjects. 10-year Follow-up From the Diagnosis." Journal of Diabetes and Its Complications, vol. 15, no. 1, 2001, pp. 24-33.
Voutilainen-Kaunisto RM, Teräsvirta ME, Uusitupa MI, et al. Occurrence and predictors of retinopathy and visual acuity in Type 2 diabetic patients and control subjects. 10-year follow-up from the diagnosis. J Diabetes Complicat. 2001;15(1):24-33.
Voutilainen-Kaunisto, R. M., Teräsvirta, M. E., Uusitupa, M. I., & Niskanen, L. K. (2001). Occurrence and predictors of retinopathy and visual acuity in Type 2 diabetic patients and control subjects. 10-year follow-up from the diagnosis. Journal of Diabetes and Its Complications, 15(1), pp. 24-33.
Voutilainen-Kaunisto RM, et al. Occurrence and Predictors of Retinopathy and Visual Acuity in Type 2 Diabetic Patients and Control Subjects. 10-year Follow-up From the Diagnosis. J Diabetes Complicat. 2001;15(1):24-33. PubMed PMID: 11259923.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Occurrence and predictors of retinopathy and visual acuity in Type 2 diabetic patients and control subjects. 10-year follow-up from the diagnosis. AU - Voutilainen-Kaunisto,R M, AU - Teräsvirta,M E, AU - Uusitupa,M I, AU - Niskanen,L K, PY - 2001/3/22/pubmed PY - 2001/5/18/medline PY - 2001/3/22/entrez SP - 24 EP - 33 JF - Journal of diabetes and its complications JO - J. Diabetes Complicat. VL - 15 IS - 1 N2 - The evolution of visual acuity and retinopathy and their risk factors in patients with newly diagnosed type 2 diabetes and in control subjects. A 10-year prospective study consisting of a representative group of 133 (70 men, 63 women) newly diagnosed type 2 diabetic patients diagnosed at health centers between 1979 and 1981 and 144 (62 men, 82 women) non-diabetic control subjects recruited from the population register. The frequency of retinopathy was determined by grading of 45 degrees fundus photographs at baseline and after 5 and 10 years. By the 10-year follow-up the diabetic patients had lower visual acuity than the control subjects. The impairment of the visual acuity correlated inversely to HbA(1C) value of the 5-year examination. The frequency of retinopathy in type 2 diabetic patients increased sharply after 5 years and at 10-year 55% of diabetic patients had signs of retinopathy. The frequency of retinopathy in the control subjects was low, but detectable. In the diabetic patients poor glycemic control was the most important predictive factor for the development of retinopathy. In the control subjects blood pressure levels were higher and microalbuminuria more common in those with than in those without retinopathy. The visual acuity deteriorated and the frequency of retinopathy increased in newly diagnosed type 2 diabetic patients with duration of disease and poor glycemic control. Interestingly, higher blood pressure levels and microalbuminuria predicted retinopathy in control subjects. SN - 1056-8727 UR - https://www.unboundmedicine.com/medline/citation/11259923/Occurrence_and_predictors_of_retinopathy_and_visual_acuity_in_Type_2_diabetic_patients_and_control_subjects__10_year_follow_up_from_the_diagnosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1056-8727(00)00126-4 DB - PRIME DP - Unbound Medicine ER -