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Gender differences in colorectal polyps and tumors.
Am J Gastroenterol 2001; 96(3):882-6AJ

Abstract

OBJECTIVES

To use a national endoscopy database (CORI) to determine 1) whether gender differences are noted in the prevalence and location of polyps and tumors; 2) whether women have a higher rate of right-sided polyps or tumors; and 3) whether age influences these results.

METHODS

CORI database from April 1, 1997 to February 19, 1999, captured in a computer-generated report, was analyzed. Polyps for this study were defined as sessile or pedunculated and as >9 mm. Tumors were defined as lesions characteristic of adenocarcinoma (mass, apple-core). Pure right-sided colon (PRS) was defined as cecum, ascending, hepatic flexure; right-sided as PRS plus the transverse colon; and left-sided as the splenic flexure, descending, sigmoid and rectum.

RESULTS

Men have a greater risk of polyps [odds ratio (OR), 1.5] and tumors (OR, 1.4) than women. The risk of finding polyps and tumors at colonoscopy increases with age, with the highest risk noted in those >69 yr of age relative to patients <50 yr of age (polyps, OR = 2.7; tumors, OR = 4.0). Right-side polyps and pure right-sided polyps as defined by the study design were noted to be more frequent than left-sided polyps in patients >60 yr of age. Women have a greater risk of developing pure right-sided polyps (OR, 1.2), tumors (OR, 1.6) and right-sided tumors (OR, 1.5) than men.

CONCLUSIONS

Men have a higher prevalence of colon polyps and tumors than women. A progressive risk of polyp or tumor formation is noted with aging. Women had a greater number of pure right-sided polyps and tumor development. Colonoscopy is needed to correctly diagnose an increasing prevalence of right-sided pathology in the elderly.

Authors+Show Affiliations

Department of Medicine, University of Nebraska Medical Center, Omaha 68198-3285, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11280569

Citation

McCashland, T M., et al. "Gender Differences in Colorectal Polyps and Tumors." The American Journal of Gastroenterology, vol. 96, no. 3, 2001, pp. 882-6.
McCashland TM, Brand R, Lyden E, et al. Gender differences in colorectal polyps and tumors. Am J Gastroenterol. 2001;96(3):882-6.
McCashland, T. M., Brand, R., Lyden, E., & de Garmo, P. (2001). Gender differences in colorectal polyps and tumors. The American Journal of Gastroenterology, 96(3), pp. 882-6.
McCashland TM, et al. Gender Differences in Colorectal Polyps and Tumors. Am J Gastroenterol. 2001;96(3):882-6. PubMed PMID: 11280569.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gender differences in colorectal polyps and tumors. AU - McCashland,T M, AU - Brand,R, AU - Lyden,E, AU - de Garmo,P, AU - ,, PY - 2001/3/31/pubmed PY - 2001/5/1/medline PY - 2001/3/31/entrez SP - 882 EP - 6 JF - The American journal of gastroenterology JO - Am. J. Gastroenterol. VL - 96 IS - 3 N2 - OBJECTIVES: To use a national endoscopy database (CORI) to determine 1) whether gender differences are noted in the prevalence and location of polyps and tumors; 2) whether women have a higher rate of right-sided polyps or tumors; and 3) whether age influences these results. METHODS: CORI database from April 1, 1997 to February 19, 1999, captured in a computer-generated report, was analyzed. Polyps for this study were defined as sessile or pedunculated and as >9 mm. Tumors were defined as lesions characteristic of adenocarcinoma (mass, apple-core). Pure right-sided colon (PRS) was defined as cecum, ascending, hepatic flexure; right-sided as PRS plus the transverse colon; and left-sided as the splenic flexure, descending, sigmoid and rectum. RESULTS: Men have a greater risk of polyps [odds ratio (OR), 1.5] and tumors (OR, 1.4) than women. The risk of finding polyps and tumors at colonoscopy increases with age, with the highest risk noted in those >69 yr of age relative to patients <50 yr of age (polyps, OR = 2.7; tumors, OR = 4.0). Right-side polyps and pure right-sided polyps as defined by the study design were noted to be more frequent than left-sided polyps in patients >60 yr of age. Women have a greater risk of developing pure right-sided polyps (OR, 1.2), tumors (OR, 1.6) and right-sided tumors (OR, 1.5) than men. CONCLUSIONS: Men have a higher prevalence of colon polyps and tumors than women. A progressive risk of polyp or tumor formation is noted with aging. Women had a greater number of pure right-sided polyps and tumor development. Colonoscopy is needed to correctly diagnose an increasing prevalence of right-sided pathology in the elderly. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/11280569/Gender_differences_in_colorectal_polyps_and_tumors_ L2 - http://Insights.ovid.com/pubmed?pmid=11280569 DB - PRIME DP - Unbound Medicine ER -