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Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols.
Eur Heart J. 2001 Apr; 22(8):684-92.EH

Abstract

AIMS

No consensus exists regarding the most appropriate exercise testing protocol for patients with congestive heart failure. This study describes the effect of exercise training on performance using three different protocols (maximal, submaximal and endurance testing) in patients with heart failure.

METHODS AND RESULTS

Thirty men (mean age 67+/-8 years) with congestive heart failure in NYHA class III (mean ejection fraction 32+/-5%) were evaluated prior to and following exercise training. A maximal exercise cycle test with gas exchange measurements, a submaximal 6 min walk test and an endurance treadmill test with blood lactate sampling were used to evaluate exercise capacity after 12 weeks of exercise training. There was a 44.6% (P<0.001) increase in work performed during the maximal cycle test, with no significant increase in peak VO(2). The distance covered by the submaximal 6 min walk test increased by 8.1% (P<0.001). Lactate measured as area under the curve during the matched work intensity treadmill endurance test was reduced by 19.5% (P<0.005).

CONCLUSION

We demonstrated a significant improvement in maximal, submaximal and endurance exercise capacity following 12 weeks of exercise training in patients with congestive heart failure. Endurance tests may be more sensitive and appropriate when assessing the efficacy of intervention in this population. Specifically, demonstration of reduced lactate production at matched work intensities suggests more efficient work and decreased dependence on anaerobic metabolism following training. Although maximal cycle tests are commonly used in clinical work, submaximal and endurance testing might be preferable for evaluating new treatment regimens in this population as they are easy to perform, are reproducible, and reflect daily tasks better than the maximal cycle test in this population.

Authors+Show Affiliations

Cardiology Division, Central Hospital in Rogaland, Stavanger, Norway.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

11286526

Citation

Larsen, A I., et al. "Assessing the Effect of Exercise Training in Men With Heart Failure; Comparison of Maximal, Submaximal and Endurance Exercise Protocols." European Heart Journal, vol. 22, no. 8, 2001, pp. 684-92.
Larsen AI, Aarsland T, Kristiansen M, et al. Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols. Eur Heart J. 2001;22(8):684-92.
Larsen, A. I., Aarsland, T., Kristiansen, M., Haugland, A., & Dickstein, K. (2001). Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols. European Heart Journal, 22(8), 684-92.
Larsen AI, et al. Assessing the Effect of Exercise Training in Men With Heart Failure; Comparison of Maximal, Submaximal and Endurance Exercise Protocols. Eur Heart J. 2001;22(8):684-92. PubMed PMID: 11286526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols. AU - Larsen,A I, AU - Aarsland,T, AU - Kristiansen,M, AU - Haugland,A, AU - Dickstein,K, PY - 2001/4/5/pubmed PY - 2001/9/6/medline PY - 2001/4/5/entrez SP - 684 EP - 92 JF - European heart journal JO - Eur. Heart J. VL - 22 IS - 8 N2 - AIMS: No consensus exists regarding the most appropriate exercise testing protocol for patients with congestive heart failure. This study describes the effect of exercise training on performance using three different protocols (maximal, submaximal and endurance testing) in patients with heart failure. METHODS AND RESULTS: Thirty men (mean age 67+/-8 years) with congestive heart failure in NYHA class III (mean ejection fraction 32+/-5%) were evaluated prior to and following exercise training. A maximal exercise cycle test with gas exchange measurements, a submaximal 6 min walk test and an endurance treadmill test with blood lactate sampling were used to evaluate exercise capacity after 12 weeks of exercise training. There was a 44.6% (P<0.001) increase in work performed during the maximal cycle test, with no significant increase in peak VO(2). The distance covered by the submaximal 6 min walk test increased by 8.1% (P<0.001). Lactate measured as area under the curve during the matched work intensity treadmill endurance test was reduced by 19.5% (P<0.005). CONCLUSION: We demonstrated a significant improvement in maximal, submaximal and endurance exercise capacity following 12 weeks of exercise training in patients with congestive heart failure. Endurance tests may be more sensitive and appropriate when assessing the efficacy of intervention in this population. Specifically, demonstration of reduced lactate production at matched work intensities suggests more efficient work and decreased dependence on anaerobic metabolism following training. Although maximal cycle tests are commonly used in clinical work, submaximal and endurance testing might be preferable for evaluating new treatment regimens in this population as they are easy to perform, are reproducible, and reflect daily tasks better than the maximal cycle test in this population. SN - 0195-668X UR - https://www.unboundmedicine.com/medline/citation/11286526/Assessing_the_effect_of_exercise_training_in_men_with_heart_failure L2 - https://academic.oup.com/eurheartj/article-lookup/doi/10.1053/euhj.2000.2286 DB - PRIME DP - Unbound Medicine ER -