Tags

Type your tag names separated by a space and hit enter

Cigarette smoking, alcohol consumption, and risk of hip fracture in women.
Arch Intern Med 2001; 161(7):983-8AI

Abstract

BACKGROUND

Previous studies regarding the impact of cigarette smoking on the risk of hip fracture in postmenopausal women have been inconsistent, suggesting different effects in different groups. The effect of alcohol intake on fracture risk is puzzling: moderate alcohol intake appears to increase bone density, and its association with hip fracture is not clear.

METHODS

To assess the associations of cigarette smoking and alcohol consumption with hip fracture risk among postmenopausal women, we conducted an analysis of a population-based case-control study from Sweden. Cases were postmenopausal women, aged 50 to 81 years, who sustained a hip fracture after minor trauma between October 1, 1993, and February 28, 1995; controls were randomly selected from a population-based register during the same period. A mailed questionnaire requesting information on lifestyle habits and medical history was used 3 months after the hip fracture for cases and simultaneously for controls. Age-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were computed by means of logistic regression.

RESULTS

Of those eligible, 1328 cases (82.5%) and 3312 controls (81.6%) responded. Compared with never smokers, current smokers had an increased risk of hip fracture (age-adjusted OR, 1.66; 95% CI, 1.41-1.95). Duration of smoking-particularly postmenopausal smoking-was more important than the amount smoked. Former smokers had a small increase in risk (age-adjusted OR, 1.15; 95% CI, 0.97-1.37) that decreased with the duration of cessation. The age-adjusted OR for women consuming alcohol was 0.80 (95% CI, 0.69-0.93).

CONCLUSIONS

Cigarette smoking is a risk factor for hip fracture among postmenopausal women; risk decreases after cessation. Alcohol consumption has a weak inverse association with risk.

Authors+Show Affiliations

7927 Rubin Bldg, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA. John.Baron@Dartmouth.edu

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11295961

Citation

Baron, J A., et al. "Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women." Archives of Internal Medicine, vol. 161, no. 7, 2001, pp. 983-8.
Baron JA, Farahmand BY, Weiderpass E, et al. Cigarette smoking, alcohol consumption, and risk of hip fracture in women. Arch Intern Med. 2001;161(7):983-8.
Baron, J. A., Farahmand, B. Y., Weiderpass, E., Michaëlsson, K., Alberts, A., Persson, I., & Ljunghall, S. (2001). Cigarette smoking, alcohol consumption, and risk of hip fracture in women. Archives of Internal Medicine, 161(7), pp. 983-8.
Baron JA, et al. Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women. Arch Intern Med. 2001 Apr 9;161(7):983-8. PubMed PMID: 11295961.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cigarette smoking, alcohol consumption, and risk of hip fracture in women. AU - Baron,J A, AU - Farahmand,B Y, AU - Weiderpass,E, AU - Michaëlsson,K, AU - Alberts,A, AU - Persson,I, AU - Ljunghall,S, PY - 2001/4/11/pubmed PY - 2001/5/5/medline PY - 2001/4/11/entrez SP - 983 EP - 8 JF - Archives of internal medicine JO - Arch. Intern. Med. VL - 161 IS - 7 N2 - BACKGROUND: Previous studies regarding the impact of cigarette smoking on the risk of hip fracture in postmenopausal women have been inconsistent, suggesting different effects in different groups. The effect of alcohol intake on fracture risk is puzzling: moderate alcohol intake appears to increase bone density, and its association with hip fracture is not clear. METHODS: To assess the associations of cigarette smoking and alcohol consumption with hip fracture risk among postmenopausal women, we conducted an analysis of a population-based case-control study from Sweden. Cases were postmenopausal women, aged 50 to 81 years, who sustained a hip fracture after minor trauma between October 1, 1993, and February 28, 1995; controls were randomly selected from a population-based register during the same period. A mailed questionnaire requesting information on lifestyle habits and medical history was used 3 months after the hip fracture for cases and simultaneously for controls. Age-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were computed by means of logistic regression. RESULTS: Of those eligible, 1328 cases (82.5%) and 3312 controls (81.6%) responded. Compared with never smokers, current smokers had an increased risk of hip fracture (age-adjusted OR, 1.66; 95% CI, 1.41-1.95). Duration of smoking-particularly postmenopausal smoking-was more important than the amount smoked. Former smokers had a small increase in risk (age-adjusted OR, 1.15; 95% CI, 0.97-1.37) that decreased with the duration of cessation. The age-adjusted OR for women consuming alcohol was 0.80 (95% CI, 0.69-0.93). CONCLUSIONS: Cigarette smoking is a risk factor for hip fracture among postmenopausal women; risk decreases after cessation. Alcohol consumption has a weak inverse association with risk. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/11295961/Cigarette_smoking_alcohol_consumption_and_risk_of_hip_fracture_in_women_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/161/pg/983 DB - PRIME DP - Unbound Medicine ER -