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Milk allergy/intolerance and atopic dermatitis in infancy and childhood.
Allergy. 2001; 56 Suppl 67:105-8.A

Abstract

Adverse reactions to cow's milk proteins are usually indicated as cow's milk allergy/intolerance (CMPA/CMPI) because no differentiation is possible on the basis of symptoms, and there is no reliable single laboratory test available for the diagnosis of CMPA or CMPI. Elimination and challenge tests for cow's milk proteins using strict, well-defined diagnostic criteria are required for the diagnosis of CMPA/CMPI. Atopic dermatitis (AD) is one of the most common symptoms of CMPA/CMPI. Approximately one third of AD children have a diagnosis of CMPA/CMPI according to elimination diet and challenge tests, and about 40-50% of children < 1 year of age with CMPA/CMPI have AD. Many children with AD and CMPA/CMPI develop a complete tolerance to CMP in a few years. Children with persisting forms of CMPA/CMPI have a more frequent history of familial atopic disease, change in CMPA/CMPI manifestations over time and very high frequency of multiple food intolerance and allergic diseases. Many children who outgrow their AD develop other allergic diseases, such as rhinitis or asthma. The simultaneous development of allergic tolerance in one organ and the intolerance or atopic disease in another organ suggest that genetic, immunologic and environmental factors play a complex role in the natural history of AD and other atopic diseases.

Authors+Show Affiliations

Centro di Allergologia, Clinica Pediatrica III - Azienda Meyer, Florence, Itlay. elio.novembre@unifi.itNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11298023

Citation

Novembre, E, and A Vierucci. "Milk Allergy/intolerance and Atopic Dermatitis in Infancy and Childhood." Allergy, vol. 56 Suppl 67, 2001, pp. 105-8.
Novembre E, Vierucci A. Milk allergy/intolerance and atopic dermatitis in infancy and childhood. Allergy. 2001;56 Suppl 67:105-8.
Novembre, E., & Vierucci, A. (2001). Milk allergy/intolerance and atopic dermatitis in infancy and childhood. Allergy, 56 Suppl 67, 105-8.
Novembre E, Vierucci A. Milk Allergy/intolerance and Atopic Dermatitis in Infancy and Childhood. Allergy. 2001;56 Suppl 67:105-8. PubMed PMID: 11298023.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Milk allergy/intolerance and atopic dermatitis in infancy and childhood. AU - Novembre,E, AU - Vierucci,A, PY - 2001/4/12/pubmed PY - 2001/8/17/medline PY - 2001/4/12/entrez SP - 105 EP - 8 JF - Allergy JO - Allergy VL - 56 Suppl 67 N2 - Adverse reactions to cow's milk proteins are usually indicated as cow's milk allergy/intolerance (CMPA/CMPI) because no differentiation is possible on the basis of symptoms, and there is no reliable single laboratory test available for the diagnosis of CMPA or CMPI. Elimination and challenge tests for cow's milk proteins using strict, well-defined diagnostic criteria are required for the diagnosis of CMPA/CMPI. Atopic dermatitis (AD) is one of the most common symptoms of CMPA/CMPI. Approximately one third of AD children have a diagnosis of CMPA/CMPI according to elimination diet and challenge tests, and about 40-50% of children < 1 year of age with CMPA/CMPI have AD. Many children with AD and CMPA/CMPI develop a complete tolerance to CMP in a few years. Children with persisting forms of CMPA/CMPI have a more frequent history of familial atopic disease, change in CMPA/CMPI manifestations over time and very high frequency of multiple food intolerance and allergic diseases. Many children who outgrow their AD develop other allergic diseases, such as rhinitis or asthma. The simultaneous development of allergic tolerance in one organ and the intolerance or atopic disease in another organ suggest that genetic, immunologic and environmental factors play a complex role in the natural history of AD and other atopic diseases. SN - 0105-4538 UR - https://www.unboundmedicine.com/medline/citation/11298023/Milk_allergy/intolerance_and_atopic_dermatitis_in_infancy_and_childhood_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&amp;sid=nlm:pubmed&amp;issn=0105-4538&amp;date=2001&amp;volume=56&amp;issue=&amp;spage=105 DB - PRIME DP - Unbound Medicine ER -