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Eosinophilic pustular folliculitis (Ofuji's disease): indomethacin as a first choice of treatment.
Clin Exp Dermatol. 2001 Mar; 26(2):179-81.CE

Abstract

Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of large follicular papules and pustules involving mainly the face. Although various treatments have been attempted for EPF, including systemic and topical steroid, diaphenylsulphone, colchicine, minocycline as well as UVB phototherapy, there is no consensus on the first choice of treatment. We report a typical case and summarize 25 patients with EPF treated in our hospital between 1978 and 1998. Indomethacin was most frequently used (12/25) and showed clinical improvement in the majority of the cases (11/12). The effect of indomethacin was usually observed within 1--2 weeks after initiation of treatment. Decrease of peripheral blood eosinophils accompanied the clinical improvement. Thus, indomethacin should be considered as a first choice of treatment for EPF.

Authors+Show Affiliations

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. ohta@med.keio.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

11298111

Citation

Ota, T, et al. "Eosinophilic Pustular Folliculitis (Ofuji's Disease): Indomethacin as a First Choice of Treatment." Clinical and Experimental Dermatology, vol. 26, no. 2, 2001, pp. 179-81.
Ota T, Hata Y, Tanikawa A, et al. Eosinophilic pustular folliculitis (Ofuji's disease): indomethacin as a first choice of treatment. Clin Exp Dermatol. 2001;26(2):179-81.
Ota, T., Hata, Y., Tanikawa, A., Amagai, M., Tanaka, M., & Nishikawa, T. (2001). Eosinophilic pustular folliculitis (Ofuji's disease): indomethacin as a first choice of treatment. Clinical and Experimental Dermatology, 26(2), 179-81.
Ota T, et al. Eosinophilic Pustular Folliculitis (Ofuji's Disease): Indomethacin as a First Choice of Treatment. Clin Exp Dermatol. 2001;26(2):179-81. PubMed PMID: 11298111.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Eosinophilic pustular folliculitis (Ofuji's disease): indomethacin as a first choice of treatment. AU - Ota,T, AU - Hata,Y, AU - Tanikawa,A, AU - Amagai,M, AU - Tanaka,M, AU - Nishikawa,T, PY - 2001/4/12/pubmed PY - 2001/6/2/medline PY - 2001/4/12/entrez SP - 179 EP - 81 JF - Clinical and experimental dermatology JO - Clin. Exp. Dermatol. VL - 26 IS - 2 N2 - Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of large follicular papules and pustules involving mainly the face. Although various treatments have been attempted for EPF, including systemic and topical steroid, diaphenylsulphone, colchicine, minocycline as well as UVB phototherapy, there is no consensus on the first choice of treatment. We report a typical case and summarize 25 patients with EPF treated in our hospital between 1978 and 1998. Indomethacin was most frequently used (12/25) and showed clinical improvement in the majority of the cases (11/12). The effect of indomethacin was usually observed within 1--2 weeks after initiation of treatment. Decrease of peripheral blood eosinophils accompanied the clinical improvement. Thus, indomethacin should be considered as a first choice of treatment for EPF. SN - 0307-6938 UR - https://www.unboundmedicine.com/medline/citation/11298111/Eosinophilic_pustular_folliculitis__Ofuji's_disease_:_indomethacin_as_a_first_choice_of_treatment_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0307-6938&date=2001&volume=26&issue=2&spage=179 DB - PRIME DP - Unbound Medicine ER -