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Hypertension and type 2 diabetes comorbidity in adults in the United States: risk of overall and regional adiposity.
Obes Res. 2001 Jan; 9(1):1-9.OR

Abstract

OBJECTIVE

To evaluate the impact of generalized, abdominal, and truncal fat deposits on the risk of hypertension and/or diabetes and to determine whether ethnic differences in these fat patterns are independently associated with increased risk for the hypertension-diabetes comorbidity (HDC).

RESEARCH METHODS AND PROCEDURES

Data (n = 7075) from the Third U.S. National Health and Nutrition Examination Survey were used for this investigation. To assess risks of hypertension and/or diabetes that were due to different fat patterns, odds ratios of men and women with various cut-points of adiposities were compared with normal subjects in logistic regression models, adjusting for age, smoking, and alcohol intake. To evaluate the contribution of ethnic differences in obesity to the risks of HDC, we compared blacks and Hispanics with whites.

RESULTS

Generalized and abdominal obesities were independently associated with increased risk of hypertension, diabetes and HDC in white, black, and Hispanic men and women. The risk of HDC due to generalized, truncal, and abdominal obesities tended to be higher in whites than blacks and Hispanics. In men, the contribution of black and Hispanic ethnicities to the increased risk of HDC due to the various obesity phenotypes was approximately 73% and approximately 61%, respectively. The corresponding values for black and Hispanic women were approximately 115% and approximately 125%, respectively.

CONCLUSIONS

In addition to advocating behavioral lifestyles to curb the epidemic of obesity among at-risk populations in the United States, there is also the need for primary health care practitioners to craft their advice to the degree and type of obesity in these at-risk groups.

Authors+Show Affiliations

Department of Community Medicine, Mercer University School of Medicine, Macon, Georgia 31207, USA. okosun_i@mercer.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11346661

Citation

Okosun, I S., et al. "Hypertension and Type 2 Diabetes Comorbidity in Adults in the United States: Risk of Overall and Regional Adiposity." Obesity Research, vol. 9, no. 1, 2001, pp. 1-9.
Okosun IS, Chandra KM, Choi S, et al. Hypertension and type 2 diabetes comorbidity in adults in the United States: risk of overall and regional adiposity. Obes Res. 2001;9(1):1-9.
Okosun, I. S., Chandra, K. M., Choi, S., Christman, J., Dever, G. E., & Prewitt, T. E. (2001). Hypertension and type 2 diabetes comorbidity in adults in the United States: risk of overall and regional adiposity. Obesity Research, 9(1), 1-9.
Okosun IS, et al. Hypertension and Type 2 Diabetes Comorbidity in Adults in the United States: Risk of Overall and Regional Adiposity. Obes Res. 2001;9(1):1-9. PubMed PMID: 11346661.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypertension and type 2 diabetes comorbidity in adults in the United States: risk of overall and regional adiposity. AU - Okosun,I S, AU - Chandra,K M, AU - Choi,S, AU - Christman,J, AU - Dever,G E, AU - Prewitt,T E, PY - 2001/5/11/pubmed PY - 2001/9/21/medline PY - 2001/5/11/entrez SP - 1 EP - 9 JF - Obesity research JO - Obes Res VL - 9 IS - 1 N2 - OBJECTIVE: To evaluate the impact of generalized, abdominal, and truncal fat deposits on the risk of hypertension and/or diabetes and to determine whether ethnic differences in these fat patterns are independently associated with increased risk for the hypertension-diabetes comorbidity (HDC). RESEARCH METHODS AND PROCEDURES: Data (n = 7075) from the Third U.S. National Health and Nutrition Examination Survey were used for this investigation. To assess risks of hypertension and/or diabetes that were due to different fat patterns, odds ratios of men and women with various cut-points of adiposities were compared with normal subjects in logistic regression models, adjusting for age, smoking, and alcohol intake. To evaluate the contribution of ethnic differences in obesity to the risks of HDC, we compared blacks and Hispanics with whites. RESULTS: Generalized and abdominal obesities were independently associated with increased risk of hypertension, diabetes and HDC in white, black, and Hispanic men and women. The risk of HDC due to generalized, truncal, and abdominal obesities tended to be higher in whites than blacks and Hispanics. In men, the contribution of black and Hispanic ethnicities to the increased risk of HDC due to the various obesity phenotypes was approximately 73% and approximately 61%, respectively. The corresponding values for black and Hispanic women were approximately 115% and approximately 125%, respectively. CONCLUSIONS: In addition to advocating behavioral lifestyles to curb the epidemic of obesity among at-risk populations in the United States, there is also the need for primary health care practitioners to craft their advice to the degree and type of obesity in these at-risk groups. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/11346661/Hypertension_and_type_2_diabetes_comorbidity_in_adults_in_the_United_States:_risk_of_overall_and_regional_adiposity_ L2 - https://doi.org/10.1038/oby.2001.1 DB - PRIME DP - Unbound Medicine ER -