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Effect of cadmium and copper on the production of citric acid by Aspergillus niger.
Folia Microbiol (Praha). 2000; 45(4):331-4.FM

Abstract

Copper and cadmium inhibited the growth as well as citric acid production (depending on the heavy metal concentrations) by citric-acid-producing Aspergillus niger. Activity of citrate synthase was connected with citrate synthesis in the absence as well as in the presence of heavy metals. The activity of aconitase, and both NAD- and NADP-isocitrate dehydrogenases was strongly inhibited by copper. The contents of DNA and proteins in the cells decreased but the contents of lipids and polysaccharides increased considerably in the presence of both heavy metals.

Authors+Show Affiliations

Tsekova K
Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Dentchev D
No affiliation info available
Todorova D
No affiliation info available

MeSH

Aconitate HydrataseAspergillus nigerCadmiumCitrate (si)-SynthaseCitric AcidCopperCulture MediaDNA, FungalDose-Response Relationship, DrugFungal ProteinsIsocitrate DehydrogenaseLipid MetabolismPolysaccharides

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11347255

Citation

Tsekova, K, et al. "Effect of Cadmium and Copper On the Production of Citric Acid By Aspergillus Niger." Folia Microbiologica, vol. 45, no. 4, 2000, pp. 331-4.
Tsekova K, Dentchev D, Todorova D. Effect of cadmium and copper on the production of citric acid by Aspergillus niger. Folia Microbiol (Praha). 2000;45(4):331-4.
Tsekova, K., Dentchev, D., & Todorova, D. (2000). Effect of cadmium and copper on the production of citric acid by Aspergillus niger. Folia Microbiologica, 45(4), 331-4.
Tsekova K, Dentchev D, Todorova D. Effect of Cadmium and Copper On the Production of Citric Acid By Aspergillus Niger. Folia Microbiol (Praha). 2000;45(4):331-4. PubMed PMID: 11347255.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of cadmium and copper on the production of citric acid by Aspergillus niger. AU - Tsekova,K, AU - Dentchev,D, AU - Todorova,D, PY - 2001/5/12/pubmed PY - 2001/9/14/medline PY - 2001/5/12/entrez SP - 331 EP - 4 JF - Folia microbiologica JO - Folia Microbiol (Praha) VL - 45 IS - 4 N2 - Copper and cadmium inhibited the growth as well as citric acid production (depending on the heavy metal concentrations) by citric-acid-producing Aspergillus niger. Activity of citrate synthase was connected with citrate synthesis in the absence as well as in the presence of heavy metals. The activity of aconitase, and both NAD- and NADP-isocitrate dehydrogenases was strongly inhibited by copper. The contents of DNA and proteins in the cells decreased but the contents of lipids and polysaccharides increased considerably in the presence of both heavy metals. SN - 0015-5632 UR - https://www.unboundmedicine.com/medline/citation/11347255/Effect_of_cadmium_and_copper_on_the_production_of_citric_acid_by_Aspergillus_niger_ DB - PRIME DP - Unbound Medicine ER -