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Adjunctive use of chlorhexidine in oral candidoses: a review.
Oral Dis. 2001 Jan; 7(1):11-7.OD

Abstract

Oral candidosis is by far the commonest human fungal infection and manifests in a variety of clinical guises. The main reason for its high incidence appears to be the multiplicity of predisposing factors, which facilitate the conversion of oral commensal Candida to a parasitic existence. Despite the availability of a number of effective antimycotics for the treatment of oral candidoses, failure of therapy is not uncommon owing to the unique environment of the oral cavity where the flushing effect of saliva and the cleansing action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. For these and other reasons chlorhexidine is widely prescribed in dentistry both as an antiseptic mouthwash and a denture disinfectant in order to supplement other antifungals. Chlorhexidine has a broad spectrum of antimicrobial activity including Candida albicans and other common non-albicans yeast species. In this review we outline the utility of chlorhexidine as an adjunct to conventional antimycotic therapy in the management of oral Candida infections.

Authors+Show Affiliations

Faculty of Dentistry, University of Hong Kong, Hong Kong, SAR.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11354914

Citation

Ellepola, A N., and L P. Samaranayake. "Adjunctive Use of Chlorhexidine in Oral Candidoses: a Review." Oral Diseases, vol. 7, no. 1, 2001, pp. 11-7.
Ellepola AN, Samaranayake LP. Adjunctive use of chlorhexidine in oral candidoses: a review. Oral Dis. 2001;7(1):11-7.
Ellepola, A. N., & Samaranayake, L. P. (2001). Adjunctive use of chlorhexidine in oral candidoses: a review. Oral Diseases, 7(1), 11-7.
Ellepola AN, Samaranayake LP. Adjunctive Use of Chlorhexidine in Oral Candidoses: a Review. Oral Dis. 2001;7(1):11-7. PubMed PMID: 11354914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adjunctive use of chlorhexidine in oral candidoses: a review. AU - Ellepola,A N, AU - Samaranayake,L P, PY - 2001/5/17/pubmed PY - 2001/6/22/medline PY - 2001/5/17/entrez SP - 11 EP - 7 JF - Oral diseases JO - Oral Dis VL - 7 IS - 1 N2 - Oral candidosis is by far the commonest human fungal infection and manifests in a variety of clinical guises. The main reason for its high incidence appears to be the multiplicity of predisposing factors, which facilitate the conversion of oral commensal Candida to a parasitic existence. Despite the availability of a number of effective antimycotics for the treatment of oral candidoses, failure of therapy is not uncommon owing to the unique environment of the oral cavity where the flushing effect of saliva and the cleansing action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. For these and other reasons chlorhexidine is widely prescribed in dentistry both as an antiseptic mouthwash and a denture disinfectant in order to supplement other antifungals. Chlorhexidine has a broad spectrum of antimicrobial activity including Candida albicans and other common non-albicans yeast species. In this review we outline the utility of chlorhexidine as an adjunct to conventional antimycotic therapy in the management of oral Candida infections. SN - 1354-523X UR - https://www.unboundmedicine.com/medline/citation/11354914/Adjunctive_use_of_chlorhexidine_in_oral_candidoses:_a_review_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1354-523X&date=2001&volume=7&issue=1&spage=11 DB - PRIME DP - Unbound Medicine ER -