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Unilateral or localized Reinke's edema (pseudocyst) as a manifestation of vocal fold paresis: the paresis podule.
Laryngoscope. 2001 Apr; 111(4 Pt 1):576-80.L

Abstract

BACKGROUND

The nosology of free-edge vocal fold lesions remains imprecise. In particular, the lesion termed pseudocyst remains enigmatic, because its histology is poorly defined and because its etiology is unknown. We define pseudocyst as a discrete, unilateral, localized area of Reinke's edema (without a capsule), usually occurring at the midportion of the free-edge striking zone.

OBJECTIVE

To report the demographic and clinical findings, as well as discuss our diagnostic and therapeutic strategies, in patients with unilateral Reinke's edema or pseudocyst.

METHODOLOGY

All patients diagnosed with unilateral Reinke's edema or pseudocyst over a 2-year period (1998-1999) were identified from the clinical database of the Center for Voice Disorders of Wake Forest University, Winston-Salem, North Carolina. The record of each patient was retrospectively reviewed.

RESULTS

Thirteen patients were identified, 12 of whom were female. The mean age was 36 years. Sixty-nine percent (9 of 13) had unilateral pseudocyst and 31% (4 of 13) had unilateral Reinke's edema. All patients had documented vocal fold paresis on laryngeal electromyography. The 9 patients with pseudocyst underwent excision of their lesions; 7 had bilateral medialization laryngoplasties, 1 had lipoinjection, and 3 did not have surgical intervention. Significant improvement was noted postoperatively on a self-administered glottal insufficiency (symptom) index (P <.001).

CONCLUSION

Unilateral Reinke's edema and localized Reinke's edema (pseudocyst) are distinct clinical entities, occurring most frequently in women in their fourth decade. The finding of unilateral Reinke's edema or pseudocyst should alert the clinician to the likelihood of vocal cord paresis. Surgical intervention with medialization laryngoplasty appears to be beneficial.

Authors+Show Affiliations

Center for Voice Disorders of Wake Forest University, Winston-Salem, North Carolina, USA.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11359123

Citation

Koufman, J A., and P C. Belafsky. "Unilateral or Localized Reinke's Edema (pseudocyst) as a Manifestation of Vocal Fold Paresis: the Paresis Podule." The Laryngoscope, vol. 111, no. 4 Pt 1, 2001, pp. 576-80.
Koufman JA, Belafsky PC. Unilateral or localized Reinke's edema (pseudocyst) as a manifestation of vocal fold paresis: the paresis podule. Laryngoscope. 2001;111(4 Pt 1):576-80.
Koufman, J. A., & Belafsky, P. C. (2001). Unilateral or localized Reinke's edema (pseudocyst) as a manifestation of vocal fold paresis: the paresis podule. The Laryngoscope, 111(4 Pt 1), 576-80.
Koufman JA, Belafsky PC. Unilateral or Localized Reinke's Edema (pseudocyst) as a Manifestation of Vocal Fold Paresis: the Paresis Podule. Laryngoscope. 2001;111(4 Pt 1):576-80. PubMed PMID: 11359123.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Unilateral or localized Reinke's edema (pseudocyst) as a manifestation of vocal fold paresis: the paresis podule. AU - Koufman,J A, AU - Belafsky,P C, PY - 2001/5/19/pubmed PY - 2001/6/23/medline PY - 2001/5/19/entrez SP - 576 EP - 80 JF - The Laryngoscope JO - Laryngoscope VL - 111 IS - 4 Pt 1 N2 - BACKGROUND: The nosology of free-edge vocal fold lesions remains imprecise. In particular, the lesion termed pseudocyst remains enigmatic, because its histology is poorly defined and because its etiology is unknown. We define pseudocyst as a discrete, unilateral, localized area of Reinke's edema (without a capsule), usually occurring at the midportion of the free-edge striking zone. OBJECTIVE: To report the demographic and clinical findings, as well as discuss our diagnostic and therapeutic strategies, in patients with unilateral Reinke's edema or pseudocyst. METHODOLOGY: All patients diagnosed with unilateral Reinke's edema or pseudocyst over a 2-year period (1998-1999) were identified from the clinical database of the Center for Voice Disorders of Wake Forest University, Winston-Salem, North Carolina. The record of each patient was retrospectively reviewed. RESULTS: Thirteen patients were identified, 12 of whom were female. The mean age was 36 years. Sixty-nine percent (9 of 13) had unilateral pseudocyst and 31% (4 of 13) had unilateral Reinke's edema. All patients had documented vocal fold paresis on laryngeal electromyography. The 9 patients with pseudocyst underwent excision of their lesions; 7 had bilateral medialization laryngoplasties, 1 had lipoinjection, and 3 did not have surgical intervention. Significant improvement was noted postoperatively on a self-administered glottal insufficiency (symptom) index (P <.001). CONCLUSION: Unilateral Reinke's edema and localized Reinke's edema (pseudocyst) are distinct clinical entities, occurring most frequently in women in their fourth decade. The finding of unilateral Reinke's edema or pseudocyst should alert the clinician to the likelihood of vocal cord paresis. Surgical intervention with medialization laryngoplasty appears to be beneficial. SN - 0023-852X UR - https://www.unboundmedicine.com/medline/citation/11359123/Unilateral_or_localized_Reinke's_edema__pseudocyst__as_a_manifestation_of_vocal_fold_paresis:_the_paresis_podule_ L2 - https://doi.org/10.1097/00005537-200104000-00005 DB - PRIME DP - Unbound Medicine ER -