Tags

Type your tag names separated by a space and hit enter

Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery.
J Am Acad Dermatol. 2001 Jun; 44(6):1004-9.JA

Abstract

BACKGROUND

Sebaceous carcinoma is an aggressive neoplasm that commonly arises from the meibomian glands of the eyelids and other sebaceous glands of the ocular adnexa. Historic data indicate a nearly 30% local recurrence rate with standard surgical excision. Excision by means of Mohs micrographic surgery may be more efficacious. However, reports documenting the effectiveness of this technique for the treatment of eyelid sebaceous carcinoma have been limited to a few cases.

OBJECTIVE

We report our experience in the treatment of ocular sebaceous carcinoma with the Mohs fresh tissue technique.

METHODS

Eighteen patients with a diagnosis of sebaceous carcinoma of the eyelid who underwent resection by means of the Mohs fresh tissue technique during the years 1988-1998 were reviewed.

RESULTS

Sixteen of the 18 patients were free of disease after an average follow-up of 37 months (11.1% recurrence rate). One patient who experienced local recurrence also had metastatic disease of the parotid lymph nodes (5.6% metastatic rate). The recurrence and metastasis were noted 9 months after excision. The other patient experienced a local recurrence 19 months postoperatively. Both patients exhibited pagetoid spread and involvement of both the upper and lower eyelid at the time of Mohs excision.

CONCLUSION

Mohs surgery offers excellent results when used as the primary treatment modality for sebaceous carcinoma of the eyelid. When compared with historic series of standard surgical excision, Mohs micrographic surgery has a significantly lower recurrence rate and metastatic rate.

Authors+Show Affiliations

Division of Dermatologic Surgery, and Department of Dermatology, Mount Sinai Medical Center, New York, NY 10029, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11369914

Citation

Spencer, J M., et al. "Sebaceous Carcinoma of the Eyelid Treated With Mohs Micrographic Surgery." Journal of the American Academy of Dermatology, vol. 44, no. 6, 2001, pp. 1004-9.
Spencer JM, Nossa R, Tse DT, et al. Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery. J Am Acad Dermatol. 2001;44(6):1004-9.
Spencer, J. M., Nossa, R., Tse, D. T., & Sequeira, M. (2001). Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery. Journal of the American Academy of Dermatology, 44(6), 1004-9.
Spencer JM, et al. Sebaceous Carcinoma of the Eyelid Treated With Mohs Micrographic Surgery. J Am Acad Dermatol. 2001;44(6):1004-9. PubMed PMID: 11369914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery. AU - Spencer,J M, AU - Nossa,R, AU - Tse,D T, AU - Sequeira,M, PY - 2001/5/23/pubmed PY - 2001/6/22/medline PY - 2001/5/23/entrez SP - 1004 EP - 9 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 44 IS - 6 N2 - BACKGROUND: Sebaceous carcinoma is an aggressive neoplasm that commonly arises from the meibomian glands of the eyelids and other sebaceous glands of the ocular adnexa. Historic data indicate a nearly 30% local recurrence rate with standard surgical excision. Excision by means of Mohs micrographic surgery may be more efficacious. However, reports documenting the effectiveness of this technique for the treatment of eyelid sebaceous carcinoma have been limited to a few cases. OBJECTIVE: We report our experience in the treatment of ocular sebaceous carcinoma with the Mohs fresh tissue technique. METHODS: Eighteen patients with a diagnosis of sebaceous carcinoma of the eyelid who underwent resection by means of the Mohs fresh tissue technique during the years 1988-1998 were reviewed. RESULTS: Sixteen of the 18 patients were free of disease after an average follow-up of 37 months (11.1% recurrence rate). One patient who experienced local recurrence also had metastatic disease of the parotid lymph nodes (5.6% metastatic rate). The recurrence and metastasis were noted 9 months after excision. The other patient experienced a local recurrence 19 months postoperatively. Both patients exhibited pagetoid spread and involvement of both the upper and lower eyelid at the time of Mohs excision. CONCLUSION: Mohs surgery offers excellent results when used as the primary treatment modality for sebaceous carcinoma of the eyelid. When compared with historic series of standard surgical excision, Mohs micrographic surgery has a significantly lower recurrence rate and metastatic rate. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/11369914/Sebaceous_carcinoma_of_the_eyelid_treated_with_Mohs_micrographic_surgery_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(01)47918-7 DB - PRIME DP - Unbound Medicine ER -