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[Triterpene saponins from Pulsatilla cernua].
Yao Xue Xue Bao. 2000 Oct; 35(10):756-9.YX

Abstract

AIM

To investigate the chemical constituents of the roots of Pulsatilla cernua (Thunb.) Bercht. et Opiz.

METHODS

Column chromatography (including D101 macroporous resin, silica gel and ODS) and HPLC were used to separate the chemical constituents whose structures were elucidated by FAB-MS, NMR (1D and 2D) and hydrolysis methods.

RESULTS

Six compounds were isolated and established as hederagenin 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranoside (pulsatilla saponin A, 1), hederagenin 3-O-beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L- arabinopyranoside (2), hederagenin' 3-O-alpha-L-rhamnopyranosyl(1-->2)[beta-D- glucopyranosyl(1-->4)]-alpha-L-arabinopyranoside (pulsatilla saponin D, 3), 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl ester (dipsacoside B, 4), 3-O-alpha-L-rhamnopyranosyl(1-->2) [beta-D-glucopyranosyl(1-->4)]-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester (cernuoside C, 5) and daucosterol (6), respectively.

CONCLUSION

Compound 5 is a new compound and named as cernuoside C. Compounds 2, 4 and 6 were isolated from Pulsatilla cernua for the first time.

Authors+Show Affiliations

Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

11372442

Citation

Zhang, Q W., et al. "[Triterpene Saponins From Pulsatilla Cernua]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 35, no. 10, 2000, pp. 756-9.
Zhang QW, Ye WC, Che CT, et al. [Triterpene saponins from Pulsatilla cernua]. Yao Xue Xue Bao. 2000;35(10):756-9.
Zhang, Q. W., Ye, W. C., Che, C. T., & Zhao, S. X. (2000). [Triterpene saponins from Pulsatilla cernua]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 35(10), 756-9.
Zhang QW, et al. [Triterpene Saponins From Pulsatilla Cernua]. Yao Xue Xue Bao. 2000;35(10):756-9. PubMed PMID: 11372442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Triterpene saponins from Pulsatilla cernua]. AU - Zhang,Q W, AU - Ye,W C, AU - Che,C T, AU - Zhao,S X, PY - 2001/5/25/pubmed PY - 2002/10/31/medline PY - 2001/5/25/entrez SP - 756 EP - 9 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 35 IS - 10 N2 - AIM: To investigate the chemical constituents of the roots of Pulsatilla cernua (Thunb.) Bercht. et Opiz. METHODS: Column chromatography (including D101 macroporous resin, silica gel and ODS) and HPLC were used to separate the chemical constituents whose structures were elucidated by FAB-MS, NMR (1D and 2D) and hydrolysis methods. RESULTS: Six compounds were isolated and established as hederagenin 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranoside (pulsatilla saponin A, 1), hederagenin 3-O-beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L- arabinopyranoside (2), hederagenin' 3-O-alpha-L-rhamnopyranosyl(1-->2)[beta-D- glucopyranosyl(1-->4)]-alpha-L-arabinopyranoside (pulsatilla saponin D, 3), 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl ester (dipsacoside B, 4), 3-O-alpha-L-rhamnopyranosyl(1-->2) [beta-D-glucopyranosyl(1-->4)]-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester (cernuoside C, 5) and daucosterol (6), respectively. CONCLUSION: Compound 5 is a new compound and named as cernuoside C. Compounds 2, 4 and 6 were isolated from Pulsatilla cernua for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/11372442/[Triterpene_saponins_from_Pulsatilla_cernua]_ DB - PRIME DP - Unbound Medicine ER -
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