TY - JOUR T1 - [Triterpene saponins from Pulsatilla cernua]. AU - Zhang,Q W, AU - Ye,W C, AU - Che,C T, AU - Zhao,S X, PY - 2001/5/25/pubmed PY - 2002/10/31/medline PY - 2001/5/25/entrez SP - 756 EP - 9 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 35 IS - 10 N2 - AIM: To investigate the chemical constituents of the roots of Pulsatilla cernua (Thunb.) Bercht. et Opiz. METHODS: Column chromatography (including D101 macroporous resin, silica gel and ODS) and HPLC were used to separate the chemical constituents whose structures were elucidated by FAB-MS, NMR (1D and 2D) and hydrolysis methods. RESULTS: Six compounds were isolated and established as hederagenin 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranoside (pulsatilla saponin A, 1), hederagenin 3-O-beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L- arabinopyranoside (2), hederagenin' 3-O-alpha-L-rhamnopyranosyl(1-->2)[beta-D- glucopyranosyl(1-->4)]-alpha-L-arabinopyranoside (pulsatilla saponin D, 3), 3-O-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl ester (dipsacoside B, 4), 3-O-alpha-L-rhamnopyranosyl(1-->2) [beta-D-glucopyranosyl(1-->4)]-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester (cernuoside C, 5) and daucosterol (6), respectively. CONCLUSION: Compound 5 is a new compound and named as cernuoside C. Compounds 2, 4 and 6 were isolated from Pulsatilla cernua for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/11372442/[Triterpene_saponins_from_Pulsatilla_cernua]_ DB - PRIME DP - Unbound Medicine ER -