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Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
Ophthalmology. 2001 Jun; 108(6):1043-9.O

Abstract

OBJECTIVE

To evaluate orbital blood flow velocities by using color Doppler imaging in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

DESIGN

Prospective, comparative case series.

PARTICIPANTS

Twenty-eight patients with pseudoexfoliation syndrome (n = 14) or pseudoexfoliation glaucoma (n = 14) and 14 healthy control participants were included.

INTERVENTION

Color Doppler imaging was used with a 7.5-MHz probe. Evaluation of the ophthalmic, central retinal, short posterior nasal, and temporal ciliary arteries was performed, and peak systolic and end diastolic flow velocities were measured. Resistive indices were calculated.

RESULTS

When compared with the control participants, patients with pseudoexfoliation syndrome showed statistically significant decreases in the mean peak systolic velocity of the central retinal artery (11.21 +/- 2.19 cm/second; P < 0.05), and end diastolic velocities of the central retinal artery (3.00 +/- 1.03 cm/second; P < 0.005), and short posterior temporal ciliary arteries (3.50 +/- 1.74 cm/second; P < 0.005), whereas mean resistive indices of the ophthalmic artery (0.75 +/- 0.06 cm/second; P < 0.005) and central retinal artery were found to have increased (0.70 +/- 0.05 cm/second; P < 0.01). Patients with pseudoexfoliation glaucoma, when compared with the control participants, showed statistically significant decreases in the mean peak systolic and end diastolic velocities and increased mean resistive indices in all vessels measured (P < 0.05). Compared with the patients with pseudoexfoliation syndrome, patients with pseudoexfoliation glaucoma showed statistically significant decreases in the mean peak systolic velocities of the ophthalmic artery (30.07 +/- 4.00 cm/second; P < 0.05) and short posterior nasal ciliary arteries (2.35 +/- 0.09 cm/second; P < 0.05), and in the mean end diastolic velocities of the ophthalmic artery (6.28 +/- 2.12 cm/second; P < 0.05), and short posterior nasal ciliary arteries (2.35 +/- 0.09 cm/second; P < 0.05). The differences in the mean resistive indices were not statistically significant between the patients with pseudoexfoliation syndrome and the ones with pseudoexfoliation glaucoma.

CONCLUSIONS

The findings suggest that hemodynamic parameters in the retrobulbar vessels were altered in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma; however, these alterations were more prominent in the latter group.

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Publisher Full Text

Authors+Show Affiliations

Yüksel N
Department of Ophthalmology, Medical School of Kocaeli University, Kocaeli, Turkey.
Karabaş VL
No affiliation info available
Arslan A
No affiliation info available
Demirci A
No affiliation info available
Cağlar Y
No affiliation info available

MeSH

AgedBlood Flow VelocityCiliary ArteriesExfoliation SyndromeEyeFemaleGlaucoma, Open-AngleHumansIntraocular PressureMaleOphthalmic ArteryProspective StudiesRegional Blood FlowRetinal ArteryUltrasonography, Doppler, ColorVisual Acuity

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11382627

Citation

Yüksel, N, et al. "Ocular Hemodynamics in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma." Ophthalmology, vol. 108, no. 6, 2001, pp. 1043-9.
Yüksel N, Karabaş VL, Arslan A, et al. Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Ophthalmology. 2001;108(6):1043-9.
Yüksel, N., Karabaş, V. L., Arslan, A., Demirci, A., & Cağlar, Y. (2001). Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Ophthalmology, 108(6), 1043-9.
Yüksel N, et al. Ocular Hemodynamics in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma. Ophthalmology. 2001;108(6):1043-9. PubMed PMID: 11382627.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. AU - Yüksel,N, AU - Karabaş,V L, AU - Arslan,A, AU - Demirci,A, AU - Cağlar,Y, PY - 2001/5/31/pubmed PY - 2001/6/22/medline PY - 2001/5/31/entrez SP - 1043 EP - 9 JF - Ophthalmology JO - Ophthalmology VL - 108 IS - 6 N2 - OBJECTIVE: To evaluate orbital blood flow velocities by using color Doppler imaging in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma. DESIGN: Prospective, comparative case series. PARTICIPANTS: Twenty-eight patients with pseudoexfoliation syndrome (n = 14) or pseudoexfoliation glaucoma (n = 14) and 14 healthy control participants were included. INTERVENTION: Color Doppler imaging was used with a 7.5-MHz probe. Evaluation of the ophthalmic, central retinal, short posterior nasal, and temporal ciliary arteries was performed, and peak systolic and end diastolic flow velocities were measured. Resistive indices were calculated. RESULTS: When compared with the control participants, patients with pseudoexfoliation syndrome showed statistically significant decreases in the mean peak systolic velocity of the central retinal artery (11.21 +/- 2.19 cm/second; P < 0.05), and end diastolic velocities of the central retinal artery (3.00 +/- 1.03 cm/second; P < 0.005), and short posterior temporal ciliary arteries (3.50 +/- 1.74 cm/second; P < 0.005), whereas mean resistive indices of the ophthalmic artery (0.75 +/- 0.06 cm/second; P < 0.005) and central retinal artery were found to have increased (0.70 +/- 0.05 cm/second; P < 0.01). Patients with pseudoexfoliation glaucoma, when compared with the control participants, showed statistically significant decreases in the mean peak systolic and end diastolic velocities and increased mean resistive indices in all vessels measured (P < 0.05). Compared with the patients with pseudoexfoliation syndrome, patients with pseudoexfoliation glaucoma showed statistically significant decreases in the mean peak systolic velocities of the ophthalmic artery (30.07 +/- 4.00 cm/second; P < 0.05) and short posterior nasal ciliary arteries (2.35 +/- 0.09 cm/second; P < 0.05), and in the mean end diastolic velocities of the ophthalmic artery (6.28 +/- 2.12 cm/second; P < 0.05), and short posterior nasal ciliary arteries (2.35 +/- 0.09 cm/second; P < 0.05). The differences in the mean resistive indices were not statistically significant between the patients with pseudoexfoliation syndrome and the ones with pseudoexfoliation glaucoma. CONCLUSIONS: The findings suggest that hemodynamic parameters in the retrobulbar vessels were altered in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma; however, these alterations were more prominent in the latter group. SN - 0161-6420 UR - https://www.unboundmedicine.com/medline/citation/11382627/Ocular_hemodynamics_in_pseudoexfoliation_syndrome_and_pseudoexfoliation_glaucoma_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(01)00572-3 DB - PRIME DP - Unbound Medicine ER -