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Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats.
Biosci Biotechnol Biochem. 2001 Apr; 65(4):774-80.BB

Abstract

Brewer's yeast cell wall (BYC) was tested on constipated male Sprague-Dawley rats that had been induced by loperamide (2 mg/kg of body weight). The preventive effect of BYC on constipation was examined and compared with that of a non-fiber diet (NF) as the control. The dose-response of BYC and the effect on defecation by constipated experimental rats were also compared with the characteristics of cellulose diet (CE) group which served as a control. Defecation was observed to be greater by the rats fed with BYC than by those fed with NF or CE. The fecal water content and level of volatile fatty acids (VFA) in the cecal contents were likewise higher in the rats fed with BYC. These results indicate that the administration of BYC was effective for improving defecation and other parameters related to defecation. These favorable effects of BYC supplemented to the diet are attributed to the fermentation ability, water holding capacity and swelling force in the large intestine.

Authors+Show Affiliations

Applied Bioresearch Center, Corporate Research and Development Department, Kirin Brewery Co., Ltd., Takasaki, Gunma, Japan. to-nakamura@kirin.co.jpNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11388452

Citation

Nakamura, T, et al. "Effects of Brewer's Yeast Cell Wall On Constipation and Defecation in Experimentally Constipated Rats." Bioscience, Biotechnology, and Biochemistry, vol. 65, no. 4, 2001, pp. 774-80.
Nakamura T, Agata K, Mizutani M, et al. Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats. Biosci Biotechnol Biochem. 2001;65(4):774-80.
Nakamura, T., Agata, K., Mizutani, M., & Iino, H. (2001). Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats. Bioscience, Biotechnology, and Biochemistry, 65(4), 774-80.
Nakamura T, et al. Effects of Brewer's Yeast Cell Wall On Constipation and Defecation in Experimentally Constipated Rats. Biosci Biotechnol Biochem. 2001;65(4):774-80. PubMed PMID: 11388452.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats. AU - Nakamura,T, AU - Agata,K, AU - Mizutani,M, AU - Iino,H, PY - 2001/6/5/pubmed PY - 2001/10/26/medline PY - 2001/6/5/entrez SP - 774 EP - 80 JF - Bioscience, biotechnology, and biochemistry JO - Biosci Biotechnol Biochem VL - 65 IS - 4 N2 - Brewer's yeast cell wall (BYC) was tested on constipated male Sprague-Dawley rats that had been induced by loperamide (2 mg/kg of body weight). The preventive effect of BYC on constipation was examined and compared with that of a non-fiber diet (NF) as the control. The dose-response of BYC and the effect on defecation by constipated experimental rats were also compared with the characteristics of cellulose diet (CE) group which served as a control. Defecation was observed to be greater by the rats fed with BYC than by those fed with NF or CE. The fecal water content and level of volatile fatty acids (VFA) in the cecal contents were likewise higher in the rats fed with BYC. These results indicate that the administration of BYC was effective for improving defecation and other parameters related to defecation. These favorable effects of BYC supplemented to the diet are attributed to the fermentation ability, water holding capacity and swelling force in the large intestine. SN - 0916-8451 UR - https://www.unboundmedicine.com/medline/citation/11388452/Effects_of_brewer's_yeast_cell_wall_on_constipation_and_defecation_in_experimentally_constipated_rats_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/bbb/65.774?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -