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Detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific IgG enzyme linked immunosorbent assay.
Mem Inst Oswaldo Cruz. 2001 May; 96(4):515-8.MI

Abstract

Angiostrongylus costaricensis may cause intestinal lesions of varied severity when it accidentally infects man in Central and South America. First-stage larvae have never been detected in stools. Therefore, a parasite-specific IgG ELISA was evaluated for the determination of the acute phase of infection. The specificity and the sensitivity of the immunoassay was shown to be 76.2% and 91.1%, respectively. Eight serum samples taken from patients with histopathological diagnosis, at different time points (3 to 15 months) after surgical treatment, showed a sharp and early decline in antibody reactivity. The titration of anti-A. costaricensis antibodies has proved to be a useful method for the diagnosis of acute abdominal angiostrongyliasis.

Authors+Show Affiliations

Laboratório de Parasitologia Molecular, Instituto de Pesquisas Biomédicas, PUCRS, Porto Alegre, RS, 90610-000, Brasil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11391424

Citation

Geiger, S M., et al. "Detection of the Acute Phase of Abdominal Angiostrongyliasis With a Parasite-specific IgG Enzyme Linked Immunosorbent Assay." Memorias Do Instituto Oswaldo Cruz, vol. 96, no. 4, 2001, pp. 515-8.
Geiger SM, Laitano AC, Sievers-Tostes C, et al. Detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific IgG enzyme linked immunosorbent assay. Mem Inst Oswaldo Cruz. 2001;96(4):515-8.
Geiger, S. M., Laitano, A. C., Sievers-Tostes, C., Agostini, A. A., Schulz-Key, H., & Graeff-Teixeira, C. (2001). Detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific IgG enzyme linked immunosorbent assay. Memorias Do Instituto Oswaldo Cruz, 96(4), 515-8.
Geiger SM, et al. Detection of the Acute Phase of Abdominal Angiostrongyliasis With a Parasite-specific IgG Enzyme Linked Immunosorbent Assay. Mem Inst Oswaldo Cruz. 2001;96(4):515-8. PubMed PMID: 11391424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific IgG enzyme linked immunosorbent assay. AU - Geiger,S M, AU - Laitano,A C, AU - Sievers-Tostes,C, AU - Agostini,A A, AU - Schulz-Key,H, AU - Graeff-Teixeira,C, PY - 2001/6/8/pubmed PY - 2001/6/29/medline PY - 2001/6/8/entrez SP - 515 EP - 8 JF - Memorias do Instituto Oswaldo Cruz JO - Mem Inst Oswaldo Cruz VL - 96 IS - 4 N2 - Angiostrongylus costaricensis may cause intestinal lesions of varied severity when it accidentally infects man in Central and South America. First-stage larvae have never been detected in stools. Therefore, a parasite-specific IgG ELISA was evaluated for the determination of the acute phase of infection. The specificity and the sensitivity of the immunoassay was shown to be 76.2% and 91.1%, respectively. Eight serum samples taken from patients with histopathological diagnosis, at different time points (3 to 15 months) after surgical treatment, showed a sharp and early decline in antibody reactivity. The titration of anti-A. costaricensis antibodies has proved to be a useful method for the diagnosis of acute abdominal angiostrongyliasis. SN - 0074-0276 UR - https://www.unboundmedicine.com/medline/citation/11391424/Detection_of_the_acute_phase_of_abdominal_angiostrongyliasis_with_a_parasite_specific_IgG_enzyme_linked_immunosorbent_assay_ L2 - https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000400012&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -