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Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
Cardiol Clin 2001; 19(2):195-202, vCC

Abstract

Prognosis in congestive heart failure is directly linked to neurohormonal activation. Angiotensin II through the activation of the renin angiotensin aldosterone system has been the principal focus therapy over the last 2 decades. New agents that target selective blockade of the angiotensin II receptor have been introduced in clinical trials for the treatment of heart failure. Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium. Aldosterone antagonists have been used in clinical trials to improve mortality in patients with chronic heart failure.

Authors+Show Affiliations

Division of Cardiology, Department of Medicine, University of Florida Health Science Center, Jacksonville, Jacksonville, Florida, USA. Alan.Miller@jax.ufl.eduNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11407105

Citation

Miller, A B., and P Srivastava. "Angiotensin Receptor Blockers and Aldosterone Antagonists in Chronic Heart Failure." Cardiology Clinics, vol. 19, no. 2, 2001, pp. 195-202, v.
Miller AB, Srivastava P. Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. Cardiol Clin. 2001;19(2):195-202, v.
Miller, A. B., & Srivastava, P. (2001). Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. Cardiology Clinics, 19(2), pp. 195-202, v.
Miller AB, Srivastava P. Angiotensin Receptor Blockers and Aldosterone Antagonists in Chronic Heart Failure. Cardiol Clin. 2001;19(2):195-202, v. PubMed PMID: 11407105.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. AU - Miller,A B, AU - Srivastava,P, PY - 2001/6/16/pubmed PY - 2001/10/26/medline PY - 2001/6/16/entrez SP - 195-202, v JF - Cardiology clinics JO - Cardiol Clin VL - 19 IS - 2 N2 - Prognosis in congestive heart failure is directly linked to neurohormonal activation. Angiotensin II through the activation of the renin angiotensin aldosterone system has been the principal focus therapy over the last 2 decades. New agents that target selective blockade of the angiotensin II receptor have been introduced in clinical trials for the treatment of heart failure. Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium. Aldosterone antagonists have been used in clinical trials to improve mortality in patients with chronic heart failure. SN - 0733-8651 UR - https://www.unboundmedicine.com/medline/citation/11407105/Angiotensin_receptor_blockers_and_aldosterone_antagonists_in_chronic_heart_failure_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8651(05)70207-1 DB - PRIME DP - Unbound Medicine ER -