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Diffuse parenchymal amyloidosis of lungs and breast. Its association with diffuse plasmacytosis and kappa-chain gammopathy.
Arch Pathol Lab Med. 1979 Oct; 103(11):583-5.AP

Abstract

A patient had systemic amyloidosis that extensively involved the lungs and breasts. Diffuse parenchymal pulmonary amyloidosis is rare but well described. Involvement of the breast in systemic amyloidosis is, however, most unusual. This patient's amyloidosis was associated with diffuse plasmacytosis and a kappa-chain gammopathy. The plasmacytosis was most prominent in the renal interstitium. Immunoperoxidase staining of the renal infiltrate and breast demonstrated IgG/kappa-staining plasma cells exclusively, suggesting that these cells were a monoclonal proliferation that contributed to the patient's M-protein and possibly to the patient's amyloid deposits.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

114145

Citation

Hardy, T J., et al. "Diffuse Parenchymal Amyloidosis of Lungs and Breast. Its Association With Diffuse Plasmacytosis and Kappa-chain Gammopathy." Archives of Pathology & Laboratory Medicine, vol. 103, no. 11, 1979, pp. 583-5.
Hardy TJ, Myerowitz RL, Bender BL. Diffuse parenchymal amyloidosis of lungs and breast. Its association with diffuse plasmacytosis and kappa-chain gammopathy. Arch Pathol Lab Med. 1979;103(11):583-5.
Hardy, T. J., Myerowitz, R. L., & Bender, B. L. (1979). Diffuse parenchymal amyloidosis of lungs and breast. Its association with diffuse plasmacytosis and kappa-chain gammopathy. Archives of Pathology & Laboratory Medicine, 103(11), 583-5.
Hardy TJ, Myerowitz RL, Bender BL. Diffuse Parenchymal Amyloidosis of Lungs and Breast. Its Association With Diffuse Plasmacytosis and Kappa-chain Gammopathy. Arch Pathol Lab Med. 1979;103(11):583-5. PubMed PMID: 114145.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffuse parenchymal amyloidosis of lungs and breast. Its association with diffuse plasmacytosis and kappa-chain gammopathy. AU - Hardy,T J, AU - Myerowitz,R L, AU - Bender,B L, PY - 1979/10/1/pubmed PY - 1979/10/1/medline PY - 1979/10/1/entrez SP - 583 EP - 5 JF - Archives of pathology & laboratory medicine JO - Arch. Pathol. Lab. Med. VL - 103 IS - 11 N2 - A patient had systemic amyloidosis that extensively involved the lungs and breasts. Diffuse parenchymal pulmonary amyloidosis is rare but well described. Involvement of the breast in systemic amyloidosis is, however, most unusual. This patient's amyloidosis was associated with diffuse plasmacytosis and a kappa-chain gammopathy. The plasmacytosis was most prominent in the renal interstitium. Immunoperoxidase staining of the renal infiltrate and breast demonstrated IgG/kappa-staining plasma cells exclusively, suggesting that these cells were a monoclonal proliferation that contributed to the patient's M-protein and possibly to the patient's amyloid deposits. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/114145/Diffuse_parenchymal_amyloidosis_of_lungs_and_breast__Its_association_with_diffuse_plasmacytosis_and_kappa_chain_gammopathy_ L2 - http://www.diseaseinfosearch.org/result/380 DB - PRIME DP - Unbound Medicine ER -