Tags

Type your tag names separated by a space and hit enter

The measurement of free erythrocyte porphyrin (FEP) as a simple means of distinguishing iron deficiency from beta-thalassemia trait in subjects with microcytosis.
J Lab Clin Med 1975; 85(1):113-9JL

Abstract

Assay of free erythrocyte porphyrin (FEP) and measurement of red cell indices were obtained in a group of subjects with iron deficiency and beta-thalassemia trait to determine if these studies cound detect these disorders and discriminate bbetween them. FEP values were increased in 90.2 per cent of subjects with iron deficiency but were within the normal range in 96.6 per cent of subjects with beta-thalassemia trait. Mean FEP values increased sligtly as transferrin saturation fell but became abnormally elevated when the transferrin saturation fell but became abnormally elevated when the transferrin saturation was less than 15 per cent. Unlike subjecs with iron deficiency in whom the mean corpuscular volume varied from 46 to 84, all individuals with beta-thalassermia trait exhibited microcytosis. In most instances, determination of FEP appears to distinguish beta-thalassemia trait from iron deficiency in patients with microcytosis.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1141725

Citation

Stockman, J A., et al. "The Measurement of Free Erythrocyte Porphyrin (FEP) as a Simple Means of Distinguishing Iron Deficiency From Beta-thalassemia Trait in Subjects With Microcytosis." The Journal of Laboratory and Clinical Medicine, vol. 85, no. 1, 1975, pp. 113-9.
Stockman JA, Weiner LS, Simon GE, et al. The measurement of free erythrocyte porphyrin (FEP) as a simple means of distinguishing iron deficiency from beta-thalassemia trait in subjects with microcytosis. J Lab Clin Med. 1975;85(1):113-9.
Stockman, J. A., Weiner, L. S., Simon, G. E., Stuart, M. J., & Oski, F. A. (1975). The measurement of free erythrocyte porphyrin (FEP) as a simple means of distinguishing iron deficiency from beta-thalassemia trait in subjects with microcytosis. The Journal of Laboratory and Clinical Medicine, 85(1), pp. 113-9.
Stockman JA, et al. The Measurement of Free Erythrocyte Porphyrin (FEP) as a Simple Means of Distinguishing Iron Deficiency From Beta-thalassemia Trait in Subjects With Microcytosis. J Lab Clin Med. 1975;85(1):113-9. PubMed PMID: 1141725.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The measurement of free erythrocyte porphyrin (FEP) as a simple means of distinguishing iron deficiency from beta-thalassemia trait in subjects with microcytosis. AU - Stockman,J A,3rd AU - Weiner,L S, AU - Simon,G E, AU - Stuart,M J, AU - Oski,F A, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 113 EP - 9 JF - The Journal of laboratory and clinical medicine JO - J. Lab. Clin. Med. VL - 85 IS - 1 N2 - Assay of free erythrocyte porphyrin (FEP) and measurement of red cell indices were obtained in a group of subjects with iron deficiency and beta-thalassemia trait to determine if these studies cound detect these disorders and discriminate bbetween them. FEP values were increased in 90.2 per cent of subjects with iron deficiency but were within the normal range in 96.6 per cent of subjects with beta-thalassemia trait. Mean FEP values increased sligtly as transferrin saturation fell but became abnormally elevated when the transferrin saturation fell but became abnormally elevated when the transferrin saturation was less than 15 per cent. Unlike subjecs with iron deficiency in whom the mean corpuscular volume varied from 46 to 84, all individuals with beta-thalassermia trait exhibited microcytosis. In most instances, determination of FEP appears to distinguish beta-thalassemia trait from iron deficiency in patients with microcytosis. SN - 0022-2143 UR - https://www.unboundmedicine.com/medline/citation/1141725/The_measurement_of_free_erythrocyte_porphyrin__FEP__as_a_simple_means_of_distinguishing_iron_deficiency_from_beta_thalassemia_trait_in_subjects_with_microcytosis_ L2 - http://www.diseaseinfosearch.org/result/814 DB - PRIME DP - Unbound Medicine ER -