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Does response to treatment of ejaculatory duct obstruction in infertile men vary with pathology?
Fertil Steril. 2001 Jul; 76(1):138-42.FS

Abstract

OBJECTIVE

To describe the pathology-specific response to transurethral resection of ejaculatory ducts (TURED) in patients with complete or partial ejaculatory duct obstruction and to evaluate the role of TURED in light of powerful assisted reproductive technologies.

DESIGN

Retrospective clinical study.

SETTING

University hospital.

PATIENT(S)

Thirty-eight infertile men with obstruction of the ejaculatory ducts.

INTERVENTION(S)

Diagnosis by transrectal ultrasonography or magnetic resonance imaging, and treatment with TURED.

MAIN OUTCOME MEASURE(S)

Changes in semen variables, pregnancy outcomes, and complication rates were analyzed before and after surgery.

RESULT(S)

Improvement in semen variables was significantly better in patients with partial obstruction (94%) of ducts than in those with complete obstruction (59%) (P=.04). Cystic obstruction, especially midline and eccentric cysts, responded best to TURED. Before surgery, all patients were candidates for IVF/ICSI; after surgery, 32% of azoospermic men and 81% of oligospermic men conceived spontaneously or were referred for IUI instead of IVF/ICSI.

CONCLUSION(S)

Ejaculatory duct obstruction due to cysts appears to respond best to TURED. In addition, TURED may decrease the need for IVF/ICSI as primary treatment in many cases. Finally, TURED may allow IVF/ICSI to be performed with ejaculated rather than surgically retrieved sperm.

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Publisher Full Text

Authors+Show Affiliations

Kadioglu A
Department of Urology, Medical Faculty of Istanbul, University of Istanbul, University of Istanbul, Istanbul, Turkey.
Cayan S
No affiliation info available
Tefekli A
No affiliation info available
Orhan I
No affiliation info available
Engin G
No affiliation info available
Turek PJ
No affiliation info available

MeSH

AdultConstriction, PathologicCystsEjaculatory DuctsFemaleFertilization in VitroGenital Diseases, MaleHumansInfertility, MaleMagnetic Resonance ImagingMaleMiddle AgedPostoperative ComplicationsPregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicUltrasonographyUrethra

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11438332

Citation

Kadioglu, A, et al. "Does Response to Treatment of Ejaculatory Duct Obstruction in Infertile Men Vary With Pathology?" Fertility and Sterility, vol. 76, no. 1, 2001, pp. 138-42.
Kadioglu A, Cayan S, Tefekli A, et al. Does response to treatment of ejaculatory duct obstruction in infertile men vary with pathology? Fertil Steril. 2001;76(1):138-42.
Kadioglu, A., Cayan, S., Tefekli, A., Orhan, I., Engin, G., & Turek, P. J. (2001). Does response to treatment of ejaculatory duct obstruction in infertile men vary with pathology? Fertility and Sterility, 76(1), 138-42.
Kadioglu A, et al. Does Response to Treatment of Ejaculatory Duct Obstruction in Infertile Men Vary With Pathology. Fertil Steril. 2001;76(1):138-42. PubMed PMID: 11438332.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does response to treatment of ejaculatory duct obstruction in infertile men vary with pathology? AU - Kadioglu,A, AU - Cayan,S, AU - Tefekli,A, AU - Orhan,I, AU - Engin,G, AU - Turek,P J, PY - 2001/7/5/pubmed PY - 2001/8/17/medline PY - 2001/7/5/entrez SP - 138 EP - 42 JF - Fertility and sterility JO - Fertil Steril VL - 76 IS - 1 N2 - OBJECTIVE: To describe the pathology-specific response to transurethral resection of ejaculatory ducts (TURED) in patients with complete or partial ejaculatory duct obstruction and to evaluate the role of TURED in light of powerful assisted reproductive technologies. DESIGN: Retrospective clinical study. SETTING: University hospital. PATIENT(S): Thirty-eight infertile men with obstruction of the ejaculatory ducts. INTERVENTION(S): Diagnosis by transrectal ultrasonography or magnetic resonance imaging, and treatment with TURED. MAIN OUTCOME MEASURE(S): Changes in semen variables, pregnancy outcomes, and complication rates were analyzed before and after surgery. RESULT(S): Improvement in semen variables was significantly better in patients with partial obstruction (94%) of ducts than in those with complete obstruction (59%) (P=.04). Cystic obstruction, especially midline and eccentric cysts, responded best to TURED. Before surgery, all patients were candidates for IVF/ICSI; after surgery, 32% of azoospermic men and 81% of oligospermic men conceived spontaneously or were referred for IUI instead of IVF/ICSI. CONCLUSION(S): Ejaculatory duct obstruction due to cysts appears to respond best to TURED. In addition, TURED may decrease the need for IVF/ICSI as primary treatment in many cases. Finally, TURED may allow IVF/ICSI to be performed with ejaculated rather than surgically retrieved sperm. SN - 0015-0282 UR - https://www.unboundmedicine.com/medline/citation/11438332/Does_response_to_treatment_of_ejaculatory_duct_obstruction_in_infertile_men_vary_with_pathology L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(01)01817-9 DB - PRIME DP - Unbound Medicine ER -