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Procyanidins from the herb of Hypericum perforatum.
Pharmazie. 2001 Jun; 56(6):509-11.P

Abstract

From the aqueous acetone extract of the herb of Hypericum perforatum the flavanols catechin (1) and epicatechin (2), and the procyanidins A2 (9), B1 (3), B2 (4), B3 (5), B5 (6), B7 (7) and C1 (8) were isolated. Their structures were established as their peracetate derivatives, on the basis of chemical and spectral evidence. The 13C NMR spectrum of the higher molecular weight polymer fraction revealed a 3',4'-dihydroxylated B-ring oxidation pattern and the 2,3-cis relative stereochemistry of the constituent flavan-3-ol units. The mean average molecular size of the polymers was estimated to be 4 to 5 flavan-3-ol units. The procyanidin pattern in comparison to that of Crataegus spec. is briefly discussed.

Authors+Show Affiliations

Institut für Pharmazeutische Biologie und Phytochemie, Westfälische Wilhelms-Universität, Münster, Germany.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11446175

Citation

Ploss, O, et al. "Procyanidins From the Herb of Hypericum Perforatum." Die Pharmazie, vol. 56, no. 6, 2001, pp. 509-11.
Ploss O, Petereit F, Nahrstedt A. Procyanidins from the herb of Hypericum perforatum. Pharmazie. 2001;56(6):509-11.
Ploss, O., Petereit, F., & Nahrstedt, A. (2001). Procyanidins from the herb of Hypericum perforatum. Die Pharmazie, 56(6), 509-11.
Ploss O, Petereit F, Nahrstedt A. Procyanidins From the Herb of Hypericum Perforatum. Pharmazie. 2001;56(6):509-11. PubMed PMID: 11446175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Procyanidins from the herb of Hypericum perforatum. AU - Ploss,O, AU - Petereit,F, AU - Nahrstedt,A, PY - 2001/7/12/pubmed PY - 2001/8/3/medline PY - 2001/7/12/entrez SP - 509 EP - 11 JF - Die Pharmazie JO - Pharmazie VL - 56 IS - 6 N2 - From the aqueous acetone extract of the herb of Hypericum perforatum the flavanols catechin (1) and epicatechin (2), and the procyanidins A2 (9), B1 (3), B2 (4), B3 (5), B5 (6), B7 (7) and C1 (8) were isolated. Their structures were established as their peracetate derivatives, on the basis of chemical and spectral evidence. The 13C NMR spectrum of the higher molecular weight polymer fraction revealed a 3',4'-dihydroxylated B-ring oxidation pattern and the 2,3-cis relative stereochemistry of the constituent flavan-3-ol units. The mean average molecular size of the polymers was estimated to be 4 to 5 flavan-3-ol units. The procyanidin pattern in comparison to that of Crataegus spec. is briefly discussed. SN - 0031-7144 UR - https://www.unboundmedicine.com/medline/citation/11446175/Procyanidins_from_the_herb_of_Hypericum_perforatum_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -