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Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity.
J Agric Food Chem. 2001 Jul; 49(7):3476-9.JA

Abstract

Centaurium erythraea Rafin. (Gentianaceae) has long been used in traditional medicine. This plant contains considerable amounts of polyphenolic compounds, namely, xanthones and phenolic acids as the main constituents. Because phenolic groups exhibit activity as radical scavengers and/or metal chelators, this study evaluated the superoxide radical scavenging properties of a lyophilized infusion obtained from C. erythraea flowering tops. Superoxide radical scavenging activity was assayed using enzymatic (xanthine/xanthine oxidase) and nonenzymatic (NADH/phenazine methosulfate) superoxide generating systems. This study provided evidence that C. erythraea exhibits interesting antioxidant properties, expressed either by the capacity to scavenge superoxide radical or to noncompetitively inhibit xanthine oxidase. The main phenolic compounds present in this extract were several esters of hydroxycinnamic acids, namely, p-coumaric, ferulic, and sinapic acids.

Authors+Show Affiliations

CEQUP/Serviço de Farmacognosia and CEQUP/Serviço de Toxicologia, Faculdade de Farmácia, Universidade do Porto, R. Aníbal Cunha 164, 4050-047 Porto, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11453794

Citation

Valentão, P, et al. "Antioxidant Activity of Centaurium Erythraea Infusion Evidenced By Its Superoxide Radical Scavenging and Xanthine Oxidase Inhibitory Activity." Journal of Agricultural and Food Chemistry, vol. 49, no. 7, 2001, pp. 3476-9.
Valentão P, Fernandes E, Carvalho F, et al. Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity. J Agric Food Chem. 2001;49(7):3476-9.
Valentão, P., Fernandes, E., Carvalho, F., Andrade, P. B., Seabra, R. M., & Bastos, M. L. (2001). Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity. Journal of Agricultural and Food Chemistry, 49(7), 3476-9.
Valentão P, et al. Antioxidant Activity of Centaurium Erythraea Infusion Evidenced By Its Superoxide Radical Scavenging and Xanthine Oxidase Inhibitory Activity. J Agric Food Chem. 2001;49(7):3476-9. PubMed PMID: 11453794.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity. AU - Valentão,P, AU - Fernandes,E, AU - Carvalho,F, AU - Andrade,P B, AU - Seabra,R M, AU - Bastos,M L, PY - 2001/7/17/pubmed PY - 2001/10/26/medline PY - 2001/7/17/entrez SP - 3476 EP - 9 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 49 IS - 7 N2 - Centaurium erythraea Rafin. (Gentianaceae) has long been used in traditional medicine. This plant contains considerable amounts of polyphenolic compounds, namely, xanthones and phenolic acids as the main constituents. Because phenolic groups exhibit activity as radical scavengers and/or metal chelators, this study evaluated the superoxide radical scavenging properties of a lyophilized infusion obtained from C. erythraea flowering tops. Superoxide radical scavenging activity was assayed using enzymatic (xanthine/xanthine oxidase) and nonenzymatic (NADH/phenazine methosulfate) superoxide generating systems. This study provided evidence that C. erythraea exhibits interesting antioxidant properties, expressed either by the capacity to scavenge superoxide radical or to noncompetitively inhibit xanthine oxidase. The main phenolic compounds present in this extract were several esters of hydroxycinnamic acids, namely, p-coumaric, ferulic, and sinapic acids. SN - 0021-8561 UR - https://www.unboundmedicine.com/medline/citation/11453794/Antioxidant_activity_of_Centaurium_erythraea_infusion_evidenced_by_its_superoxide_radical_scavenging_and_xanthine_oxidase_inhibitory_activity_ L2 - https://doi.org/10.1021/jf001145s DB - PRIME DP - Unbound Medicine ER -