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[Eosinophilic pustular folliculitis in childhood].
An Esp Pediatr 2001; 55(2):154-8AE

Abstract

BACKGROUND

Eosinophilic pustular folliculitis (EPF) is an inflammatory disorder of unknown etiology. In infants this disorder is characterized by recurrent episodes of sterile pustules primarily or exclusively involving the scalp with occasional involvement of the face, trunk and extremities. There are few reports of EPF in children.

OBJECTIVE

To describe the clinical features and evolution of four pediatric patients and to discuss the main differential diagnoses.

METHODS

Biopsy specimens were examined, pustules were cultured and laboratory tests were analyzed.

RESULTS

Four patients (3 males and 1 female) aged 7-18 months presented with self limiting recurrent pruritic papules and pustules on the scalp. In one patient, the lesions were mainly localized on the extremities. Cultures for bacteria, fungi and viruses were negative. No systemic disease was found. Topical steroids were effective in three patients but pustules recurred after treatment was stopped. Cetirizine and Hydroxacen were administered in two corticoid-resistant patients with fair response. No other systemic therapy was administered. Peripheral eosinophilia was detected in three patients.

CONCLUSIONS

EPF in infants seems to be a clearly defined entity. Although few cases have been described in children, this dermatosis is undoubtedly more frequent than suggested by the literature. Consequently, pediatricians should be aware of its existence.

Authors+Show Affiliations

Unidad de Dermatología y Servicio de Anatomía Patológica, Consorcio Sanitario del Parc Taulí, Sabadell, Barcelona, Spain. jluelmo@cspt.es

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

11472668

Citation

Luelmo Aguilar, J, and A Sáez Artacho. "[Eosinophilic Pustular Folliculitis in Childhood]." Anales Espanoles De Pediatria, vol. 55, no. 2, 2001, pp. 154-8.
Luelmo Aguilar J, Sáez Artacho A. [Eosinophilic pustular folliculitis in childhood]. An Esp Pediatr. 2001;55(2):154-8.
Luelmo Aguilar, J., & Sáez Artacho, A. (2001). [Eosinophilic pustular folliculitis in childhood]. Anales Espanoles De Pediatria, 55(2), pp. 154-8.
Luelmo Aguilar J, Sáez Artacho A. [Eosinophilic Pustular Folliculitis in Childhood]. An Esp Pediatr. 2001;55(2):154-8. PubMed PMID: 11472668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Eosinophilic pustular folliculitis in childhood]. AU - Luelmo Aguilar,J, AU - Sáez Artacho,A, PY - 2001/7/27/pubmed PY - 2001/10/12/medline PY - 2001/7/27/entrez SP - 154 EP - 8 JF - Anales espanoles de pediatria JO - An. Esp. Pediatr. VL - 55 IS - 2 N2 - BACKGROUND: Eosinophilic pustular folliculitis (EPF) is an inflammatory disorder of unknown etiology. In infants this disorder is characterized by recurrent episodes of sterile pustules primarily or exclusively involving the scalp with occasional involvement of the face, trunk and extremities. There are few reports of EPF in children. OBJECTIVE: To describe the clinical features and evolution of four pediatric patients and to discuss the main differential diagnoses. METHODS: Biopsy specimens were examined, pustules were cultured and laboratory tests were analyzed. RESULTS: Four patients (3 males and 1 female) aged 7-18 months presented with self limiting recurrent pruritic papules and pustules on the scalp. In one patient, the lesions were mainly localized on the extremities. Cultures for bacteria, fungi and viruses were negative. No systemic disease was found. Topical steroids were effective in three patients but pustules recurred after treatment was stopped. Cetirizine and Hydroxacen were administered in two corticoid-resistant patients with fair response. No other systemic therapy was administered. Peripheral eosinophilia was detected in three patients. CONCLUSIONS: EPF in infants seems to be a clearly defined entity. Although few cases have been described in children, this dermatosis is undoubtedly more frequent than suggested by the literature. Consequently, pediatricians should be aware of its existence. SN - 0302-4342 UR - https://www.unboundmedicine.com/medline/citation/11472668/[Eosinophilic_pustular_folliculitis_in_childhood]_ L2 - http://www.diseaseinfosearch.org/result/2561 DB - PRIME DP - Unbound Medicine ER -