Tags

Type your tag names separated by a space and hit enter

[Expression of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome].
Zhonghua Fu Chan Ke Za Zhi. 1999 Nov; 34(11):652-4.ZF

Abstract

OBJECTIVE

To study the expression and implication of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome (PCOS).

METHODS

The apoptosis regulatory protein expression of bcl-2 and bax protein in endometrium were investigated by immunohistochemical method in 18 PCOS and 27 normal subjects proliferative phase 10 and secretory phase 17.

RESULTS

Bcl-2 expression was higher in PCOS than that both in control proliferative phase (P < 0.05) and secretory phase (P < 0.001). Bax expression was not significantly different between PCOS and controls (P > 0.05).

CONCLUSIONS

The higher bcl-2 protein expression inhibits the endometrium apoptosis and plays an important role in the abnormal proliferative changes of endometrium in PCOS.

Authors+Show Affiliations

Third Hospital of Beijing Medical University, Beijing 100083.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

11479944

Citation

Chen, Y, et al. "[Expression of Apoptosis Regulatory Protein Bcl-2 and Bax in Endometrium of Polycystic Ovary Syndrome]." Zhonghua Fu Chan Ke Za Zhi, vol. 34, no. 11, 1999, pp. 652-4.
Chen Y, Wang Y, Li M. [Expression of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome]. Zhonghua Fu Chan Ke Za Zhi. 1999;34(11):652-4.
Chen, Y., Wang, Y., & Li, M. (1999). [Expression of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome]. Zhonghua Fu Chan Ke Za Zhi, 34(11), 652-4.
Chen Y, Wang Y, Li M. [Expression of Apoptosis Regulatory Protein Bcl-2 and Bax in Endometrium of Polycystic Ovary Syndrome]. Zhonghua Fu Chan Ke Za Zhi. 1999;34(11):652-4. PubMed PMID: 11479944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Expression of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome]. AU - Chen,Y, AU - Wang,Y, AU - Li,M, PY - 2001/8/2/pubmed PY - 2001/8/17/medline PY - 2001/8/2/entrez SP - 652 EP - 4 JF - Zhonghua fu chan ke za zhi JO - Zhonghua Fu Chan Ke Za Zhi VL - 34 IS - 11 N2 - OBJECTIVE: To study the expression and implication of apoptosis regulatory protein bcl-2 and bax in endometrium of polycystic ovary syndrome (PCOS). METHODS: The apoptosis regulatory protein expression of bcl-2 and bax protein in endometrium were investigated by immunohistochemical method in 18 PCOS and 27 normal subjects proliferative phase 10 and secretory phase 17. RESULTS: Bcl-2 expression was higher in PCOS than that both in control proliferative phase (P < 0.05) and secretory phase (P < 0.001). Bax expression was not significantly different between PCOS and controls (P > 0.05). CONCLUSIONS: The higher bcl-2 protein expression inhibits the endometrium apoptosis and plays an important role in the abnormal proliferative changes of endometrium in PCOS. SN - 0529-567X UR - https://www.unboundmedicine.com/medline/citation/11479944/[Expression_of_apoptosis_regulatory_protein_bcl_2_and_bax_in_endometrium_of_polycystic_ovary_syndrome]_ L2 - https://medlineplus.gov/polycysticovarysyndrome.html DB - PRIME DP - Unbound Medicine ER -