Tags

Type your tag names separated by a space and hit enter

Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon.
Hum Pathol. 2001 Jul; 32(7):750-2.HP

Abstract

Leptospirosis, a disease acquired by exposure to contaminated water, is characterized by fever accompanied by various symptoms, including abdominal pain. An acute febrile illness occurred in athletes who participated in an Illinois triathlon in which the swimming event took place in a freshwater lake. Of 876 athletes, 120 sought medical care and 22 were hospitalized. Two of the athletes had their gallbladders removed because of abdominal pain and clinical suspicion of acute cholecystitis. We applied an immunohistochemical test for leptospirosis to these gallbladders and demonstrated bacterial antigens staining (granular and filamentous patterns) around blood vessels of the serosa and muscle layer. Rare intact bacteria were seen in 1 case. These results show that leptospirosis can mimic the clinical symptoms of acute cholecystitis. If a cholecystectomy is performed in febrile patients with suspicious environmental or animal exposure, pathologic studies for leptospirosis on formalin-fixed, paraffin-embedded tissues may be of great value.

Authors+Show Affiliations

Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, and Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11486175

Citation

Guarner, J, et al. "Leptospirosis Mimicking Acute Cholecystitis Among Athletes Participating in a Triathlon." Human Pathology, vol. 32, no. 7, 2001, pp. 750-2.
Guarner J, Shieh WJ, Morgan J, et al. Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon. Hum Pathol. 2001;32(7):750-2.
Guarner, J., Shieh, W. J., Morgan, J., Bragg, S. L., Bajani, M. D., Tappero, J. W., & Zaki, S. R. (2001). Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon. Human Pathology, 32(7), 750-2.
Guarner J, et al. Leptospirosis Mimicking Acute Cholecystitis Among Athletes Participating in a Triathlon. Hum Pathol. 2001;32(7):750-2. PubMed PMID: 11486175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon. AU - Guarner,J, AU - Shieh,W J, AU - Morgan,J, AU - Bragg,S L, AU - Bajani,M D, AU - Tappero,J W, AU - Zaki,S R, PY - 2001/8/4/pubmed PY - 2001/8/24/medline PY - 2001/8/4/entrez SP - 750 EP - 2 JF - Human pathology JO - Hum Pathol VL - 32 IS - 7 N2 - Leptospirosis, a disease acquired by exposure to contaminated water, is characterized by fever accompanied by various symptoms, including abdominal pain. An acute febrile illness occurred in athletes who participated in an Illinois triathlon in which the swimming event took place in a freshwater lake. Of 876 athletes, 120 sought medical care and 22 were hospitalized. Two of the athletes had their gallbladders removed because of abdominal pain and clinical suspicion of acute cholecystitis. We applied an immunohistochemical test for leptospirosis to these gallbladders and demonstrated bacterial antigens staining (granular and filamentous patterns) around blood vessels of the serosa and muscle layer. Rare intact bacteria were seen in 1 case. These results show that leptospirosis can mimic the clinical symptoms of acute cholecystitis. If a cholecystectomy is performed in febrile patients with suspicious environmental or animal exposure, pathologic studies for leptospirosis on formalin-fixed, paraffin-embedded tissues may be of great value. SN - 0046-8177 UR - https://www.unboundmedicine.com/medline/citation/11486175/Leptospirosis_mimicking_acute_cholecystitis_among_athletes_participating_in_a_triathlon_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0046-8177(01)42948-0 DB - PRIME DP - Unbound Medicine ER -