Tags

Type your tag names separated by a space and hit enter

Mucocele-like tumor of the breast associated with ductal carcinoma in situ and mucinous carcinoma : a case report.
J Korean Med Sci. 2001 Aug; 16(4):516-8.JK

Abstract

Mucocele-like tumor (MLT) of the breast is a rare neoplasm. Although this lesion was considered benign when first described, the concept of a pathologic continuum with mucinous carcinoma was evident in subsequent reports. Only a few cases of MLT have been reported in Korea. We describe a case of MLT associated with ductal carcinoma in situ and mucinous carcinoma in a 34-yr-old female. Histological examination showed multiple mucus-filled cysts of varying size. Extravasated mucin was present in the surrounding stroma. The lining of the cysts in most areas were of flat or cuboidal epithelium and devoid of cellular atypia. The lining epithelium showed proliferative change ranging from atypical ductal hyperplasia to ductal carcinoma in situ, micropapillary type. A microscopic focus of mucinous carcinoma within MLT was also noted. None of the lesions exhibited epithelial reactivity for p53 protein. The patient is alive and well without evidence of disease 54 months after initial treatment. This case supports the concept that MLT encompasses a spectrum of pathologic lesions including benign tumor, atypical ductal hyperplasia, ductal carcinoma in situ, and mucinous carcinoma.

Authors+Show Affiliations

Department of Pathology, Seonam University, College of Medicine, Namwon, Korea. jshinlee@hanmail.netNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11511801

Citation

Lee, J S., et al. "Mucocele-like Tumor of the Breast Associated With Ductal Carcinoma in Situ and Mucinous Carcinoma : a Case Report." Journal of Korean Medical Science, vol. 16, no. 4, 2001, pp. 516-8.
Lee JS, Kim HS, Jung JJ, et al. Mucocele-like tumor of the breast associated with ductal carcinoma in situ and mucinous carcinoma : a case report. J Korean Med Sci. 2001;16(4):516-8.
Lee, J. S., Kim, H. S., Jung, J. J., & Lee, M. C. (2001). Mucocele-like tumor of the breast associated with ductal carcinoma in situ and mucinous carcinoma : a case report. Journal of Korean Medical Science, 16(4), 516-8.
Lee JS, et al. Mucocele-like Tumor of the Breast Associated With Ductal Carcinoma in Situ and Mucinous Carcinoma : a Case Report. J Korean Med Sci. 2001;16(4):516-8. PubMed PMID: 11511801.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mucocele-like tumor of the breast associated with ductal carcinoma in situ and mucinous carcinoma : a case report. AU - Lee,J S, AU - Kim,H S, AU - Jung,J J, AU - Lee,M C, PY - 2001/8/21/pubmed PY - 2001/10/26/medline PY - 2001/8/21/entrez SP - 516 EP - 8 JF - Journal of Korean medical science JO - J Korean Med Sci VL - 16 IS - 4 N2 - Mucocele-like tumor (MLT) of the breast is a rare neoplasm. Although this lesion was considered benign when first described, the concept of a pathologic continuum with mucinous carcinoma was evident in subsequent reports. Only a few cases of MLT have been reported in Korea. We describe a case of MLT associated with ductal carcinoma in situ and mucinous carcinoma in a 34-yr-old female. Histological examination showed multiple mucus-filled cysts of varying size. Extravasated mucin was present in the surrounding stroma. The lining of the cysts in most areas were of flat or cuboidal epithelium and devoid of cellular atypia. The lining epithelium showed proliferative change ranging from atypical ductal hyperplasia to ductal carcinoma in situ, micropapillary type. A microscopic focus of mucinous carcinoma within MLT was also noted. None of the lesions exhibited epithelial reactivity for p53 protein. The patient is alive and well without evidence of disease 54 months after initial treatment. This case supports the concept that MLT encompasses a spectrum of pathologic lesions including benign tumor, atypical ductal hyperplasia, ductal carcinoma in situ, and mucinous carcinoma. SN - 1011-8934 UR - https://www.unboundmedicine.com/medline/citation/11511801/Mucocele_like_tumor_of_the_breast_associated_with_ductal_carcinoma_in_situ_and_mucinous_carcinoma_:_a_case_report_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2001.16.4.516 DB - PRIME DP - Unbound Medicine ER -