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Pituitary apoplexy caused by luteinizing hormone-releasing hormone in prolactin-producing adenoma.
Intern Med. 2001 Aug; 40(8):747-50.IM

Abstract

We report a case in which pituitary apoplexy developed shortly after an intravenous (i.v.) injection of luteinizing hormone-releasing hormone (LH-RH). A 56-year-old man with prolactin-producing pituitary tumor complained of severe headache, visual field loss and facial nerve palsy shortly after LH-RH test. Magnetic resonance image (MRI) revealed a hemorrhage in the pituitary adenoma. He showed dramatic improvement in his symptoms after decompression surgery. These findings suggest a causal relationship between the i.v. injection of LH-RH and pituitary apoplexy. Possible pituitary apoplexy should be kept in mind during pituitary testing.

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Authors+Show Affiliations

Hiroi N
First Department of Internal Medicine, Toho University School of Medicine, Tokyo.
Ichijo T
No affiliation info available
Shimojo M
No affiliation info available
Ueshiba H
No affiliation info available
Tsuboi K
No affiliation info available
Miyachi Y
No affiliation info available

MeSH

Facial ParalysisGonadotropin-Releasing HormoneGonadotropins, PituitaryHeadacheHormonesHumansInjections, IntravenousMagnetic Resonance ImagingMaleMiddle AgedPituitary ApoplexyPituitary NeoplasmsProlactinomaVision Disorders

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11518116

Citation

Hiroi, N, et al. "Pituitary Apoplexy Caused By Luteinizing Hormone-releasing Hormone in Prolactin-producing Adenoma." Internal Medicine (Tokyo, Japan), vol. 40, no. 8, 2001, pp. 747-50.
Hiroi N, Ichijo T, Shimojo M, et al. Pituitary apoplexy caused by luteinizing hormone-releasing hormone in prolactin-producing adenoma. Intern Med. 2001;40(8):747-50.
Hiroi, N., Ichijo, T., Shimojo, M., Ueshiba, H., Tsuboi, K., & Miyachi, Y. (2001). Pituitary apoplexy caused by luteinizing hormone-releasing hormone in prolactin-producing adenoma. Internal Medicine (Tokyo, Japan), 40(8), 747-50.
Hiroi N, et al. Pituitary Apoplexy Caused By Luteinizing Hormone-releasing Hormone in Prolactin-producing Adenoma. Intern Med. 2001;40(8):747-50. PubMed PMID: 11518116.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pituitary apoplexy caused by luteinizing hormone-releasing hormone in prolactin-producing adenoma. AU - Hiroi,N, AU - Ichijo,T, AU - Shimojo,M, AU - Ueshiba,H, AU - Tsuboi,K, AU - Miyachi,Y, PY - 2001/8/24/pubmed PY - 2002/1/29/medline PY - 2001/8/24/entrez SP - 747 EP - 50 JF - Internal medicine (Tokyo, Japan) JO - Intern Med VL - 40 IS - 8 N2 - We report a case in which pituitary apoplexy developed shortly after an intravenous (i.v.) injection of luteinizing hormone-releasing hormone (LH-RH). A 56-year-old man with prolactin-producing pituitary tumor complained of severe headache, visual field loss and facial nerve palsy shortly after LH-RH test. Magnetic resonance image (MRI) revealed a hemorrhage in the pituitary adenoma. He showed dramatic improvement in his symptoms after decompression surgery. These findings suggest a causal relationship between the i.v. injection of LH-RH and pituitary apoplexy. Possible pituitary apoplexy should be kept in mind during pituitary testing. SN - 0918-2918 UR - https://www.unboundmedicine.com/medline/citation/11518116/Pituitary_apoplexy_caused_by_luteinizing_hormone_releasing_hormone_in_prolactin_producing_adenoma_ L2 - https://joi.jlc.jst.go.jp/JST.Journalarchive/internalmedicine1992/40.747?from=PubMed DB - PRIME DP - Unbound Medicine ER -