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Plasma antioxidant capacity of HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols.
Eur J Clin Nutr. 2001 Sep; 55(9):786-92.EJ

Abstract

OBJECTIVE

To investigate whether antioxidant polyphenols from fruit juices or a fruit-vegetable-concentrate increase the plasma antioxidant capacity in HIV-infected and healthy subjects.

DESIGN

Twenty-three HIV-seropositive and 18 seronegative adults were randomized to ingest either 1 l of fruit juice or 30 ml fruit-vegetable-concentrate per day over 16 weeks in addition to their normal Western diet.

METHODS

Plasma antioxidant capacity was determined as Trolox equivalent antioxidant capacity (TEAC) at baseline, after 1 and 16 weeks of intervention, and after a 6 week washout.

RESULTS

There was no difference in plasma antioxidant capacity between HIV-infected and healthy subjects at baseline (P=0.1). After 16 weeks of intervention TEAC increased in HIV-positive subjects with both types of polyphenol supplementation (juice, 1.38+/-0.07 to 1.42+/-0.04 mM, P=0.034; concentrate, 1.40+/-0.09 to 1.46+/-0.08 mM, P=0.025). TEAC was not altered by either type of supplementation in HIV-seronegative subjects.

CONCLUSION

Plasma antioxidant capacity can be increased by long-term ingestion of polyphenols from fruit juices or fruit-vegetable-concentrate in HIV-seropositive but not in HIV-seronegative subjects.

SPONSORSHIP

This study was supported by a grant and Cellagon aurum from HG Berner GmbH, Altenholz, and fruit juices from Eckes Granini GmbH & Co. KG, Nieder-Olm.

Authors+Show Affiliations

School of Medicine, Department of Hemostasis and Transfusion Medicine, University of Düsseldorf, Düsseldorf, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11528495

Citation

Arendt, B M., et al. "Plasma Antioxidant Capacity of HIV-seropositive and Healthy Subjects During Long-term Ingestion of Fruit Juices or a Fruit-vegetable-concentrate Containing Antioxidant Polyphenols." European Journal of Clinical Nutrition, vol. 55, no. 9, 2001, pp. 786-92.
Arendt BM, Boetzer AM, Lemoch H, et al. Plasma antioxidant capacity of HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols. Eur J Clin Nutr. 2001;55(9):786-92.
Arendt, B. M., Boetzer, A. M., Lemoch, H., Winkler, P., Rockstroh, J. K., Berthold, H. K., Spengler, U., & Goerlich, R. (2001). Plasma antioxidant capacity of HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols. European Journal of Clinical Nutrition, 55(9), 786-92.
Arendt BM, et al. Plasma Antioxidant Capacity of HIV-seropositive and Healthy Subjects During Long-term Ingestion of Fruit Juices or a Fruit-vegetable-concentrate Containing Antioxidant Polyphenols. Eur J Clin Nutr. 2001;55(9):786-92. PubMed PMID: 11528495.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma antioxidant capacity of HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols. AU - Arendt,B M, AU - Boetzer,A M, AU - Lemoch,H, AU - Winkler,P, AU - Rockstroh,J K, AU - Berthold,H K, AU - Spengler,U, AU - Goerlich,R, PY - 2000/07/11/received PY - 2001/03/07/revised PY - 2001/03/08/accepted PY - 2001/8/31/pubmed PY - 2001/11/3/medline PY - 2001/8/31/entrez SP - 786 EP - 92 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 55 IS - 9 N2 - OBJECTIVE: To investigate whether antioxidant polyphenols from fruit juices or a fruit-vegetable-concentrate increase the plasma antioxidant capacity in HIV-infected and healthy subjects. DESIGN: Twenty-three HIV-seropositive and 18 seronegative adults were randomized to ingest either 1 l of fruit juice or 30 ml fruit-vegetable-concentrate per day over 16 weeks in addition to their normal Western diet. METHODS: Plasma antioxidant capacity was determined as Trolox equivalent antioxidant capacity (TEAC) at baseline, after 1 and 16 weeks of intervention, and after a 6 week washout. RESULTS: There was no difference in plasma antioxidant capacity between HIV-infected and healthy subjects at baseline (P=0.1). After 16 weeks of intervention TEAC increased in HIV-positive subjects with both types of polyphenol supplementation (juice, 1.38+/-0.07 to 1.42+/-0.04 mM, P=0.034; concentrate, 1.40+/-0.09 to 1.46+/-0.08 mM, P=0.025). TEAC was not altered by either type of supplementation in HIV-seronegative subjects. CONCLUSION: Plasma antioxidant capacity can be increased by long-term ingestion of polyphenols from fruit juices or fruit-vegetable-concentrate in HIV-seropositive but not in HIV-seronegative subjects. SPONSORSHIP: This study was supported by a grant and Cellagon aurum from HG Berner GmbH, Altenholz, and fruit juices from Eckes Granini GmbH & Co. KG, Nieder-Olm. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/11528495/Plasma_antioxidant_capacity_of_HIV_seropositive_and_healthy_subjects_during_long_term_ingestion_of_fruit_juices_or_a_fruit_vegetable_concentrate_containing_antioxidant_polyphenols_ L2 - http://dx.doi.org/10.1038/sj.ejcn.1601227 DB - PRIME DP - Unbound Medicine ER -