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A pilot study of gabapentin as treatment for acquired nystagmus.
Neuroophthalmology. 1996 Apr; 16(2):107-13.N

Abstract

The effects of the anticonvulsant gabapentin were measured on vision and eve movements in three patients with acquired pendular nystagmus. In two patients, the nystagmus was associated with multiple sclerosis and, in the other, it followed brainstem stroke. A single oral 600 mg dose of gabapentin produced improvement of vision due to changes in ocular oscillations in all three patients. The effect was sustained after five weeks of treatment in two patients who elected to continue taking gabapentin 900-1500 mg/day. The results of this pilot study suggest that a controlled trial of gabapentin should be conducted to evaluate its role in the treatment of acquired forms of nystagmus.

Authors+Show Affiliations

Department of Neurology, Case Western Reserve University, Cleveland, OH, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11539872

Citation

Stahl, J S., et al. "A Pilot Study of Gabapentin as Treatment for Acquired Nystagmus." Neuro-ophthalmology (Aeolus Press), vol. 16, no. 2, 1996, pp. 107-13.
Stahl JS, Rottach KG, Averbuch-Heller L, et al. A pilot study of gabapentin as treatment for acquired nystagmus. Neuroophthalmology. 1996;16(2):107-13.
Stahl, J. S., Rottach, K. G., Averbuch-Heller, L., von Maydell, R. D., Collins, S. D., & Leigh, R. J. (1996). A pilot study of gabapentin as treatment for acquired nystagmus. Neuro-ophthalmology (Aeolus Press), 16(2), 107-13.
Stahl JS, et al. A Pilot Study of Gabapentin as Treatment for Acquired Nystagmus. Neuroophthalmology. 1996;16(2):107-13. PubMed PMID: 11539872.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A pilot study of gabapentin as treatment for acquired nystagmus. AU - Stahl,J S, AU - Rottach,K G, AU - Averbuch-Heller,L, AU - von Maydell,R D, AU - Collins,S D, AU - Leigh,R J, PY - 1996/4/1/pubmed PY - 2001/9/11/medline PY - 1996/4/1/entrez SP - 107 EP - 13 JF - Neuro-ophthalmology (Aeolus Press) JO - Neuroophthalmology VL - 16 IS - 2 N2 - The effects of the anticonvulsant gabapentin were measured on vision and eve movements in three patients with acquired pendular nystagmus. In two patients, the nystagmus was associated with multiple sclerosis and, in the other, it followed brainstem stroke. A single oral 600 mg dose of gabapentin produced improvement of vision due to changes in ocular oscillations in all three patients. The effect was sustained after five weeks of treatment in two patients who elected to continue taking gabapentin 900-1500 mg/day. The results of this pilot study suggest that a controlled trial of gabapentin should be conducted to evaluate its role in the treatment of acquired forms of nystagmus. SN - 0165-8107 UR - https://www.unboundmedicine.com/medline/citation/11539872/A_pilot_study_of_gabapentin_as_treatment_for_acquired_nystagmus_ DB - PRIME DP - Unbound Medicine ER -