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Sesquiterpenoid derivatives from Ferula ferulaeoides [correction of ferulioides]. V.
Chem Pharm Bull (Tokyo). 2001 Sep; 49(9):1072-6.CP

Abstract

Nine novel prenyl-dihydrofurocoumarin-type sesquiterpenoid derivatives, 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadien-6-onyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4-methyl-5- (4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2R*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadien-6-onyl]-furo-[3,2-c]coumarin, and 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, were isolated from the roots of Ferula ferulaeoides [corrected]. The structures were established by comprehensive spectral analysis. The biosynthetic pathway leading to these prenyl-furocoumarin-type sesquiterpenoids is proposed based on their structures.

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Authors+Show Affiliations

Isaka K
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Nagatsu A
No affiliation info available
Ondognii P
No affiliation info available
Zevgeegiin O
No affiliation info available
Gombosurengyin P
No affiliation info available
Davgiin K
No affiliation info available
Kojima K
No affiliation info available
Ogihara Y
No affiliation info available

MeSH

FerulaHydroxylationMagnetic Resonance SpectroscopyPlant ExtractsPlant RootsSesquiterpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11558588

Citation

Isaka, K, et al. "Sesquiterpenoid Derivatives From Ferula Ferulaeoides [correction of Ferulioides]. V." Chemical & Pharmaceutical Bulletin, vol. 49, no. 9, 2001, pp. 1072-6.
Isaka K, Nagatsu A, Ondognii P, et al. Sesquiterpenoid derivatives from Ferula ferulaeoides [correction of ferulioides]. V. Chem Pharm Bull (Tokyo). 2001;49(9):1072-6.
Isaka, K., Nagatsu, A., Ondognii, P., Zevgeegiin, O., Gombosurengyin, P., Davgiin, K., Kojima, K., & Ogihara, Y. (2001). Sesquiterpenoid derivatives from Ferula ferulaeoides [correction of ferulioides]. V. Chemical & Pharmaceutical Bulletin, 49(9), 1072-6.
Isaka K, et al. Sesquiterpenoid Derivatives From Ferula Ferulaeoides [correction of Ferulioides]. V. Chem Pharm Bull (Tokyo). 2001;49(9):1072-6. PubMed PMID: 11558588.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sesquiterpenoid derivatives from Ferula ferulaeoides [correction of ferulioides]. V. AU - Isaka,K, AU - Nagatsu,A, AU - Ondognii,P, AU - Zevgeegiin,O, AU - Gombosurengyin,P, AU - Davgiin,K, AU - Kojima,K, AU - Ogihara,Y, PY - 2001/9/18/pubmed PY - 2002/2/22/medline PY - 2001/9/18/entrez SP - 1072 EP - 6 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 49 IS - 9 N2 - Nine novel prenyl-dihydrofurocoumarin-type sesquiterpenoid derivatives, 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadien-6-onyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4-methyl-5- (4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2R*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[3,2-c]coumarin, 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadien-6-onyl]-furo-[3,2-c]coumarin, and 2,3-dihydro-7-methoxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E)-pentenyl]-furo[3,2-c]coumarin, were isolated from the roots of Ferula ferulaeoides [corrected]. The structures were established by comprehensive spectral analysis. The biosynthetic pathway leading to these prenyl-furocoumarin-type sesquiterpenoids is proposed based on their structures. SN - 0009-2363 UR - https://www.unboundmedicine.com/medline/citation/11558588/Sesquiterpenoid_derivatives_from_Ferula_ferulaeoides_[correction_of_ferulioides]__V_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/cpb/49.1072?from=PubMed DB - PRIME DP - Unbound Medicine ER -