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Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment.
CA Cancer J Clin 2001 Sep-Oct; 51(5):290-315CC

Abstract

Chemotherapy- and radiotherapy-induced oral mucositis represents a therapeutic challenge frequently encountered in cancer patients. This side effect causes significant morbidity and may delay the treatment plan, as well as increase therapeutic expenses. The pathogenesis of this debilitating side effect can be attributed to the direct mucosal toxicity of cytotoxic agents and ionizing radiation and to indirect mucosal damage caused by a concomitant inflammatory reaction exacerbated in the presence of neutropenia, and the emergence of bacterial, mycotic, and viral infections. The prophylactic and therapeutic armamentarium for the treatment of oral mucositis consists of locally and systemically applied nonpharmacological measures and pharmacotherapeutics.

Authors+Show Affiliations

Clinical Division of Oncology, Department of Medicine I, University Hospital of Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11577493

Citation

Köstler, W J., et al. "Oral Mucositis Complicating Chemotherapy And/or Radiotherapy: Options for Prevention and Treatment." CA: a Cancer Journal for Clinicians, vol. 51, no. 5, 2001, pp. 290-315.
Köstler WJ, Hejna M, Wenzel C, et al. Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. CA Cancer J Clin. 2001;51(5):290-315.
Köstler, W. J., Hejna, M., Wenzel, C., & Zielinski, C. C. (2001). Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. CA: a Cancer Journal for Clinicians, 51(5), pp. 290-315.
Köstler WJ, et al. Oral Mucositis Complicating Chemotherapy And/or Radiotherapy: Options for Prevention and Treatment. CA Cancer J Clin. 2001;51(5):290-315. PubMed PMID: 11577493.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. AU - Köstler,W J, AU - Hejna,M, AU - Wenzel,C, AU - Zielinski,C C, PY - 2001/10/2/pubmed PY - 2001/10/12/medline PY - 2001/10/2/entrez SP - 290 EP - 315 JF - CA: a cancer journal for clinicians JO - CA Cancer J Clin VL - 51 IS - 5 N2 - Chemotherapy- and radiotherapy-induced oral mucositis represents a therapeutic challenge frequently encountered in cancer patients. This side effect causes significant morbidity and may delay the treatment plan, as well as increase therapeutic expenses. The pathogenesis of this debilitating side effect can be attributed to the direct mucosal toxicity of cytotoxic agents and ionizing radiation and to indirect mucosal damage caused by a concomitant inflammatory reaction exacerbated in the presence of neutropenia, and the emergence of bacterial, mycotic, and viral infections. The prophylactic and therapeutic armamentarium for the treatment of oral mucositis consists of locally and systemically applied nonpharmacological measures and pharmacotherapeutics. SN - 0007-9235 UR - https://www.unboundmedicine.com/medline/citation/11577493/Oral_mucositis_complicating_chemotherapy_and/or_radiotherapy:_options_for_prevention_and_treatment_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-9235&date=2001&volume=51&issue=5&spage=290 DB - PRIME DP - Unbound Medicine ER -