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The malaria threat.
Med Trop (Mars). 2001; 61(1):63-6.MT

Abstract

The British experience of the past two decades indicates that fixed-schedule chemoprophylaxis is difficult because of the variety of epidemiological situations and increasing incidence of drug resistance. Of the 110 cases of malaria contracted in Kenya between 1982 and 1996, 74% were due to Plasmodium falciparum. Of the 45 malaria infections contracted in Belize, 84% were due to Plasmodium vivax. In 1985 the fixed drug combination of chloroquine base 300 mg weekly plus proguanil 200 mg daily was adopted as standard chemoprophylaxis for use in all parts of the world where chemoresistant Plasmodium falciparum had been observed. Mefloquine was recommended as first-line prophylaxis in Papua New Guinea in 1986 and in East Africa in 1993. Doxycycline hyclate was prescribed in September 1999 when a Gurkha company was deployed on peacekeeping duties to East Timor, but its effectiveness has not yet been evaluated. Chemoprophylaxis must be combined with non-drug antimalaria technologies, especially insecticide-treated bed nets.

Authors+Show Affiliations

Surgeon General's Department, Ministry of Defence, Whitehall, London SW1A 2HB, UK. AshleyCroft@compuserve.comNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11584659

Citation

Croft, A M., and K G. Geary. "The Malaria Threat." Medecine Tropicale : Revue Du Corps De Sante Colonial, vol. 61, no. 1, 2001, pp. 63-6.
Croft AM, Geary KG. The malaria threat. Med Trop (Mars). 2001;61(1):63-6.
Croft, A. M., & Geary, K. G. (2001). The malaria threat. Medecine Tropicale : Revue Du Corps De Sante Colonial, 61(1), 63-6.
Croft AM, Geary KG. The Malaria Threat. Med Trop (Mars). 2001;61(1):63-6. PubMed PMID: 11584659.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The malaria threat. AU - Croft,A M, AU - Geary,K G, PY - 2001/10/5/pubmed PY - 2002/1/5/medline PY - 2001/10/5/entrez SP - 63 EP - 6 JF - Medecine tropicale : revue du Corps de sante colonial JO - Med Trop (Mars) VL - 61 IS - 1 N2 - The British experience of the past two decades indicates that fixed-schedule chemoprophylaxis is difficult because of the variety of epidemiological situations and increasing incidence of drug resistance. Of the 110 cases of malaria contracted in Kenya between 1982 and 1996, 74% were due to Plasmodium falciparum. Of the 45 malaria infections contracted in Belize, 84% were due to Plasmodium vivax. In 1985 the fixed drug combination of chloroquine base 300 mg weekly plus proguanil 200 mg daily was adopted as standard chemoprophylaxis for use in all parts of the world where chemoresistant Plasmodium falciparum had been observed. Mefloquine was recommended as first-line prophylaxis in Papua New Guinea in 1986 and in East Africa in 1993. Doxycycline hyclate was prescribed in September 1999 when a Gurkha company was deployed on peacekeeping duties to East Timor, but its effectiveness has not yet been evaluated. Chemoprophylaxis must be combined with non-drug antimalaria technologies, especially insecticide-treated bed nets. SN - 0025-682X UR - https://www.unboundmedicine.com/medline/citation/11584659/The_malaria_threat_ L2 - https://www.diseaseinfosearch.org/result/4415 DB - PRIME DP - Unbound Medicine ER -