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Co-expression of P2X receptor subunits on rat nodose neurons that bind the isolectin GS-I-B4.
Neuroreport 2001; 12(13):2995-7N

Abstract

Triple fluorescent histochemistry was used to describe the types of overlap in visceral sensory neurons (nodose ganglion) for the labeling of the isolectin B4 from Griffonia simplicifolia type one (GS-I-B4) and their immunoreactivity (IR) for two of the ATP receptor subunits (P2X1/3 or P2X2/3). The vast majority of nodose neurons expressed GS-I-B4-binding and most of these displayed P2X receptor IR. Most of the P2X-IR was co-expressed on these individual nodose neurons (P2X1/P2X3 or P2X2/P2X3). A very small subpopulation of neurons that were GS-I-B4 negative but P2X positive displayed a very high relative intensity of P2X3-IR. The functional role that these expression patterns play in visceral sensory processing is currently unclear.

Authors+Show Affiliations

Department of Physiological Sciences, College of Veterinary Medicine and The Evelyn F. And William L. McKnight Brain Institute, University of Florida, Gainesville, Box 100144, FL 32610-0144, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11588618

Citation

Hubscher, C H., et al. "Co-expression of P2X Receptor Subunits On Rat Nodose Neurons That Bind the Isolectin GS-I-B4." Neuroreport, vol. 12, no. 13, 2001, pp. 2995-7.
Hubscher CH, Petruska JC, Rau KK, et al. Co-expression of P2X receptor subunits on rat nodose neurons that bind the isolectin GS-I-B4. Neuroreport. 2001;12(13):2995-7.
Hubscher, C. H., Petruska, J. C., Rau, K. K., & Johnson, R. D. (2001). Co-expression of P2X receptor subunits on rat nodose neurons that bind the isolectin GS-I-B4. Neuroreport, 12(13), pp. 2995-7.
Hubscher CH, et al. Co-expression of P2X Receptor Subunits On Rat Nodose Neurons That Bind the Isolectin GS-I-B4. Neuroreport. 2001 Sep 17;12(13):2995-7. PubMed PMID: 11588618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Co-expression of P2X receptor subunits on rat nodose neurons that bind the isolectin GS-I-B4. AU - Hubscher,C H, AU - Petruska,J C, AU - Rau,K K, AU - Johnson,R D, PY - 2001/10/6/pubmed PY - 2002/1/5/medline PY - 2001/10/6/entrez SP - 2995 EP - 7 JF - Neuroreport JO - Neuroreport VL - 12 IS - 13 N2 - Triple fluorescent histochemistry was used to describe the types of overlap in visceral sensory neurons (nodose ganglion) for the labeling of the isolectin B4 from Griffonia simplicifolia type one (GS-I-B4) and their immunoreactivity (IR) for two of the ATP receptor subunits (P2X1/3 or P2X2/3). The vast majority of nodose neurons expressed GS-I-B4-binding and most of these displayed P2X receptor IR. Most of the P2X-IR was co-expressed on these individual nodose neurons (P2X1/P2X3 or P2X2/P2X3). A very small subpopulation of neurons that were GS-I-B4 negative but P2X positive displayed a very high relative intensity of P2X3-IR. The functional role that these expression patterns play in visceral sensory processing is currently unclear. SN - 0959-4965 UR - https://www.unboundmedicine.com/medline/citation/11588618/Co_expression_of_P2X_receptor_subunits_on_rat_nodose_neurons_that_bind_the_isolectin_GS_I_B4_ L2 - http://Insights.ovid.com/pubmed?pmid=11588618 DB - PRIME DP - Unbound Medicine ER -