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[Hereditary non polyposis colorectal cancer].
Ann Med Interne (Paris). 2001 Sep; 152(5):317-21.AM

Abstract

Hereditary non polyposis colorectal cancer (HNPCC) is characterized by an excess of early colorectal carcinomas, preferentially located on the ascending colon, associated with a variety of extracolonic cancers. The recent demonstration of germline mutations in DNA mismatch repair genes in HNPCC patients enhanced the interest due to the syndrome. Molecular genetic testing of HNPCC has become available, and should help physicians to recommend specific modalities for the surveillance and the management of patients with such a high cancer risk.

Authors+Show Affiliations

Service d'Hépato-Gastro-Entérologie, Hôpital Cochin, 24, rue du Faubourg-Saint-Jacques, 75014 Paris, France.

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

11593143

Citation

Dieumegard, B. "[Hereditary Non Polyposis Colorectal Cancer]." Annales De Medecine Interne, vol. 152, no. 5, 2001, pp. 317-21.
Dieumegard B. [Hereditary non polyposis colorectal cancer]. Ann Med Interne (Paris). 2001;152(5):317-21.
Dieumegard, B. (2001). [Hereditary non polyposis colorectal cancer]. Annales De Medecine Interne, 152(5), 317-21.
Dieumegard B. [Hereditary Non Polyposis Colorectal Cancer]. Ann Med Interne (Paris). 2001;152(5):317-21. PubMed PMID: 11593143.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hereditary non polyposis colorectal cancer]. A1 - Dieumegard,B, PY - 2001/10/11/pubmed PY - 2002/1/5/medline PY - 2001/10/11/entrez SP - 317 EP - 21 JF - Annales de medecine interne JO - Ann Med Interne (Paris) VL - 152 IS - 5 N2 - Hereditary non polyposis colorectal cancer (HNPCC) is characterized by an excess of early colorectal carcinomas, preferentially located on the ascending colon, associated with a variety of extracolonic cancers. The recent demonstration of germline mutations in DNA mismatch repair genes in HNPCC patients enhanced the interest due to the syndrome. Molecular genetic testing of HNPCC has become available, and should help physicians to recommend specific modalities for the surveillance and the management of patients with such a high cancer risk. SN - 0003-410X UR - https://www.unboundmedicine.com/medline/citation/11593143/[Hereditary_non_polyposis_colorectal_cancer]_ L2 - http://www.diseaseinfosearch.org/result/5249 DB - PRIME DP - Unbound Medicine ER -