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Localisation of mRNAs for diamine oxidase and histamine receptors H1 and H2, at the feto-maternal interface of human pregnancy.
Inflamm Res. 2001 Sep; 50(9):449-52.IR

Abstract

OBJECTIVE AND DESIGN

To localise mRNAs for the histamine receptors H1, H2 and H3, and for diamine oxidase, in the placenta and decidua of the human feto-maternal interface.

MATERIALS AND METHODS

Complementary DNA for each mRNA of interest was amplified by polymerase chain reaction. Sub-cloned sequences were used to prepare probes for in situ hybridisation, and these were employed to localise the expression of mRNAs for histamine receptors H1 and H2, and for diamine oxidase.

RESULTS

mRNA for histamine receptors H1 and H2, and for diamine oxidase could be detected at the feto-maternal interface of human pregnancy, and localised to both decidual and placental cells.

CONCLUSION

The co-expression of these receptors and DAO is consistent with a role for histamine at the feto-maternal interface of human pregnancy.

Authors+Show Affiliations

Wolfson Institute of Health Science, Thames Valley University, London, UK. obed.brew@tvu.ac.nkNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11603849

Citation

Brew, O B., and M H. Sullivan. "Localisation of mRNAs for Diamine Oxidase and Histamine Receptors H1 and H2, at the Feto-maternal Interface of Human Pregnancy." Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], vol. 50, no. 9, 2001, pp. 449-52.
Brew OB, Sullivan MH. Localisation of mRNAs for diamine oxidase and histamine receptors H1 and H2, at the feto-maternal interface of human pregnancy. Inflamm Res. 2001;50(9):449-52.
Brew, O. B., & Sullivan, M. H. (2001). Localisation of mRNAs for diamine oxidase and histamine receptors H1 and H2, at the feto-maternal interface of human pregnancy. Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 50(9), 449-52.
Brew OB, Sullivan MH. Localisation of mRNAs for Diamine Oxidase and Histamine Receptors H1 and H2, at the Feto-maternal Interface of Human Pregnancy. Inflamm Res. 2001;50(9):449-52. PubMed PMID: 11603849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Localisation of mRNAs for diamine oxidase and histamine receptors H1 and H2, at the feto-maternal interface of human pregnancy. AU - Brew,O B, AU - Sullivan,M H, PY - 2001/10/18/pubmed PY - 2002/3/22/medline PY - 2001/10/18/entrez SP - 449 EP - 52 JF - Inflammation research : official journal of the European Histamine Research Society ... [et al.] JO - Inflamm. Res. VL - 50 IS - 9 N2 - OBJECTIVE AND DESIGN: To localise mRNAs for the histamine receptors H1, H2 and H3, and for diamine oxidase, in the placenta and decidua of the human feto-maternal interface. MATERIALS AND METHODS: Complementary DNA for each mRNA of interest was amplified by polymerase chain reaction. Sub-cloned sequences were used to prepare probes for in situ hybridisation, and these were employed to localise the expression of mRNAs for histamine receptors H1 and H2, and for diamine oxidase. RESULTS: mRNA for histamine receptors H1 and H2, and for diamine oxidase could be detected at the feto-maternal interface of human pregnancy, and localised to both decidual and placental cells. CONCLUSION: The co-expression of these receptors and DAO is consistent with a role for histamine at the feto-maternal interface of human pregnancy. SN - 1023-3830 UR - https://www.unboundmedicine.com/medline/citation/11603849/Localisation_of_mRNAs_for_diamine_oxidase_and_histamine_receptors_H1_and_H2_at_the_feto_maternal_interface_of_human_pregnancy_ L2 - https://dx.doi.org/10.1007/PL00000269 DB - PRIME DP - Unbound Medicine ER -