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Negative predictive value of sonography with mammography in patients with palpable breast lesions.
AJR Am J Roentgenol. 2001 Nov; 177(5):1167-70.AA

Abstract

OBJECTIVE

This study was performed to determine the negative predictive value of sonography with mammography in evaluating palpable breast lesions.

MATERIALS AND METHODS

Four hundred twenty patients with 455 palpable breast lesions were retrospectively identified from our mammography database as having negative mammographic and sonographic results. For patients diagnosed with breast cancer, images and medical records were reviewed to determine whether the palpable lesion evaluated on sonography and mammography corresponded to the patient's breast cancer. On the basis of the number of breast cancers that correlated to the palpable areas imaged, the negative predictive value of sonography with mammography was determined.

RESULTS

Sixty-two of the 420 patients in the study group were already diagnosed with breast carcinoma, and eight new carcinomas were diagnosed during the study period. Only one of six ipsilateral cancers corresponded to a palpable lesion that had a negative imaging evaluation. This lesion was diagnosed as an invasive lobular cancer, hard and fixed at physical examination. Imaging and clinical follow-up of the remaining patients showed no abnormality at the sites of previously investigated palpable abnormalities. The mean imaging follow-up was 25 months. The negative predictive value of sonography and mammography in the setting of a palpable lesion was 99.8%.

CONCLUSION

The negative predictive value of sonography with mammography is high, and together these imaging modalities can be reassuring if follow-up is planned when the physical examination is not highly suspicious. However, if the physical examination is suspicious, biopsy should not be delayed.

Authors+Show Affiliations

Department of Radiology, Duke University Medical Center, P.O. Box 3808, Rm. 24244B, Durham, NC 27710, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11641195

Citation

Soo, M S., et al. "Negative Predictive Value of Sonography With Mammography in Patients With Palpable Breast Lesions." AJR. American Journal of Roentgenology, vol. 177, no. 5, 2001, pp. 1167-70.
Soo MS, Rosen EL, Baker JA, et al. Negative predictive value of sonography with mammography in patients with palpable breast lesions. AJR Am J Roentgenol. 2001;177(5):1167-70.
Soo, M. S., Rosen, E. L., Baker, J. A., Vo, T. T., & Boyd, B. A. (2001). Negative predictive value of sonography with mammography in patients with palpable breast lesions. AJR. American Journal of Roentgenology, 177(5), 1167-70.
Soo MS, et al. Negative Predictive Value of Sonography With Mammography in Patients With Palpable Breast Lesions. AJR Am J Roentgenol. 2001;177(5):1167-70. PubMed PMID: 11641195.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Negative predictive value of sonography with mammography in patients with palpable breast lesions. AU - Soo,M S, AU - Rosen,E L, AU - Baker,J A, AU - Vo,T T, AU - Boyd,B A, PY - 2001/10/20/pubmed PY - 2002/1/5/medline PY - 2001/10/20/entrez SP - 1167 EP - 70 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 177 IS - 5 N2 - OBJECTIVE: This study was performed to determine the negative predictive value of sonography with mammography in evaluating palpable breast lesions. MATERIALS AND METHODS: Four hundred twenty patients with 455 palpable breast lesions were retrospectively identified from our mammography database as having negative mammographic and sonographic results. For patients diagnosed with breast cancer, images and medical records were reviewed to determine whether the palpable lesion evaluated on sonography and mammography corresponded to the patient's breast cancer. On the basis of the number of breast cancers that correlated to the palpable areas imaged, the negative predictive value of sonography with mammography was determined. RESULTS: Sixty-two of the 420 patients in the study group were already diagnosed with breast carcinoma, and eight new carcinomas were diagnosed during the study period. Only one of six ipsilateral cancers corresponded to a palpable lesion that had a negative imaging evaluation. This lesion was diagnosed as an invasive lobular cancer, hard and fixed at physical examination. Imaging and clinical follow-up of the remaining patients showed no abnormality at the sites of previously investigated palpable abnormalities. The mean imaging follow-up was 25 months. The negative predictive value of sonography and mammography in the setting of a palpable lesion was 99.8%. CONCLUSION: The negative predictive value of sonography with mammography is high, and together these imaging modalities can be reassuring if follow-up is planned when the physical examination is not highly suspicious. However, if the physical examination is suspicious, biopsy should not be delayed. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/11641195/Negative_predictive_value_of_sonography_with_mammography_in_patients_with_palpable_breast_lesions_ L2 - https://www.ajronline.org/doi/10.2214/ajr.177.5.1771167 DB - PRIME DP - Unbound Medicine ER -