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Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up.
Acta Chir Scand. 1975; 141(3):203-7.AC

Abstract

Sixty-three patients with duodenal ulcer were operated upon with selective proximal vagotomy (SPV). In 34 patients the vagotomy was combined with a pyloroplasty (PP). Before and after operation the acid secretion was investigated after Histalog (50 mg) stimulation. Insulin tests were performed 4-6 weeks, 1 year, and 3 years after operation. One and 3 years after operation ESR, Hb, SeFe, Protein, Albumin, Calcium, and Alkaline phosphatases were determined. One patient developed gastric retention and 3 got relapses during the first year. At reoperation, overlooked vagal branches in the region of the cardia were found. Five patients developed a minor anemia and 2 sideropenia, which is less than after truncal vagotomy and PP. The operation caused a highly significant reduction in acid output after Histalog stimulation. The postoperative insulin test was graded according to Bachrach: 49 were complete, 12 extensive but incomplete, and 2 incomplete. During the second hour after stimulation a probably significant increase was noted in the acid output between the postoperative and the one-year investigation. Between the one- and the three-years tests a significant increase was found during the first hour after insulin stimulation and a probably significant increase during the second hour. The gastric emptying of a composite fluid test meal was significantly faster after operation than before in patients where the insulin stimulation did not give rise to any acid production.

Authors

Moberg S
No affiliation info available
Hedenstedt S
No affiliation info available

MeSH

AdolescentAdultAgedAnemiaDumping SyndromeDuodenal UlcerFemaleFollow-Up StudiesGastric JuiceGastrointestinal MotilityHumansInsulinMaleMiddle AgedPostoperative ComplicationsPylorusPyrazolesTransferrinVagotomy

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

1166744

Citation

Moberg, S, and S Hedenstedt. "Clinical, Secretory and Motor Effects of Selective Proximal Vagotomy. a Three-year Follow-up." Acta Chirurgica Scandinavica, vol. 141, no. 3, 1975, pp. 203-7.
Moberg S, Hedenstedt S. Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. Acta Chir Scand. 1975;141(3):203-7.
Moberg, S., & Hedenstedt, S. (1975). Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. Acta Chirurgica Scandinavica, 141(3), 203-7.
Moberg S, Hedenstedt S. Clinical, Secretory and Motor Effects of Selective Proximal Vagotomy. a Three-year Follow-up. Acta Chir Scand. 1975;141(3):203-7. PubMed PMID: 1166744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. AU - Moberg,S, AU - Hedenstedt,S, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 203 EP - 7 JF - Acta chirurgica Scandinavica JO - Acta Chir Scand VL - 141 IS - 3 N2 - Sixty-three patients with duodenal ulcer were operated upon with selective proximal vagotomy (SPV). In 34 patients the vagotomy was combined with a pyloroplasty (PP). Before and after operation the acid secretion was investigated after Histalog (50 mg) stimulation. Insulin tests were performed 4-6 weeks, 1 year, and 3 years after operation. One and 3 years after operation ESR, Hb, SeFe, Protein, Albumin, Calcium, and Alkaline phosphatases were determined. One patient developed gastric retention and 3 got relapses during the first year. At reoperation, overlooked vagal branches in the region of the cardia were found. Five patients developed a minor anemia and 2 sideropenia, which is less than after truncal vagotomy and PP. The operation caused a highly significant reduction in acid output after Histalog stimulation. The postoperative insulin test was graded according to Bachrach: 49 were complete, 12 extensive but incomplete, and 2 incomplete. During the second hour after stimulation a probably significant increase was noted in the acid output between the postoperative and the one-year investigation. Between the one- and the three-years tests a significant increase was found during the first hour after insulin stimulation and a probably significant increase during the second hour. The gastric emptying of a composite fluid test meal was significantly faster after operation than before in patients where the insulin stimulation did not give rise to any acid production. SN - 0001-5482 UR - https://www.unboundmedicine.com/medline/citation/1166744/Clinical_secretory_and_motor_effects_of_selective_proximal_vagotomy__A_three_year_follow_up_ DB - PRIME DP - Unbound Medicine ER -