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Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up.
Acta Chir Scand. 1975; 141(3):203-7.AC

Abstract

Sixty-three patients with duodenal ulcer were operated upon with selective proximal vagotomy (SPV). In 34 patients the vagotomy was combined with a pyloroplasty (PP). Before and after operation the acid secretion was investigated after Histalog (50 mg) stimulation. Insulin tests were performed 4-6 weeks, 1 year, and 3 years after operation. One and 3 years after operation ESR, Hb, SeFe, Protein, Albumin, Calcium, and Alkaline phosphatases were determined. One patient developed gastric retention and 3 got relapses during the first year. At reoperation, overlooked vagal branches in the region of the cardia were found. Five patients developed a minor anemia and 2 sideropenia, which is less than after truncal vagotomy and PP. The operation caused a highly significant reduction in acid output after Histalog stimulation. The postoperative insulin test was graded according to Bachrach: 49 were complete, 12 extensive but incomplete, and 2 incomplete. During the second hour after stimulation a probably significant increase was noted in the acid output between the postoperative and the one-year investigation. Between the one- and the three-years tests a significant increase was found during the first hour after insulin stimulation and a probably significant increase during the second hour. The gastric emptying of a composite fluid test meal was significantly faster after operation than before in patients where the insulin stimulation did not give rise to any acid production.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

1166744

Citation

Moberg, S, and S Hedenstedt. "Clinical, Secretory and Motor Effects of Selective Proximal Vagotomy. a Three-year Follow-up." Acta Chirurgica Scandinavica, vol. 141, no. 3, 1975, pp. 203-7.
Moberg S, Hedenstedt S. Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. Acta Chir Scand. 1975;141(3):203-7.
Moberg, S., & Hedenstedt, S. (1975). Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. Acta Chirurgica Scandinavica, 141(3), 203-7.
Moberg S, Hedenstedt S. Clinical, Secretory and Motor Effects of Selective Proximal Vagotomy. a Three-year Follow-up. Acta Chir Scand. 1975;141(3):203-7. PubMed PMID: 1166744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up. AU - Moberg,S, AU - Hedenstedt,S, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 203 EP - 7 JF - Acta chirurgica Scandinavica JO - Acta Chir Scand VL - 141 IS - 3 N2 - Sixty-three patients with duodenal ulcer were operated upon with selective proximal vagotomy (SPV). In 34 patients the vagotomy was combined with a pyloroplasty (PP). Before and after operation the acid secretion was investigated after Histalog (50 mg) stimulation. Insulin tests were performed 4-6 weeks, 1 year, and 3 years after operation. One and 3 years after operation ESR, Hb, SeFe, Protein, Albumin, Calcium, and Alkaline phosphatases were determined. One patient developed gastric retention and 3 got relapses during the first year. At reoperation, overlooked vagal branches in the region of the cardia were found. Five patients developed a minor anemia and 2 sideropenia, which is less than after truncal vagotomy and PP. The operation caused a highly significant reduction in acid output after Histalog stimulation. The postoperative insulin test was graded according to Bachrach: 49 were complete, 12 extensive but incomplete, and 2 incomplete. During the second hour after stimulation a probably significant increase was noted in the acid output between the postoperative and the one-year investigation. Between the one- and the three-years tests a significant increase was found during the first hour after insulin stimulation and a probably significant increase during the second hour. The gastric emptying of a composite fluid test meal was significantly faster after operation than before in patients where the insulin stimulation did not give rise to any acid production. SN - 0001-5482 UR - https://www.unboundmedicine.com/medline/citation/1166744/Clinical_secretory_and_motor_effects_of_selective_proximal_vagotomy__A_three_year_follow_up_ DB - PRIME DP - Unbound Medicine ER -