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Latent autoimmune diabetes in adults (LADA) and autoimmune thyroiditis.
Endocr Regul 2001; 35(3):167-72ER

Abstract

Latent autoimmune diabetes in adults (LADA) is characterized by clinical presentation as type 2 diabetes after 25 years of age, initial control achieved with diet or oral hypoglycaemic agents during at least 6 months, presence of autoantibodies (first of all GADA) and some immunogenetic features of diabetes mellitus type 1. In patients with an autoimmune endocrine disease, which could be also autoimmune diabetes, there is a high risk of development of another autoimmune endocrine disorder. The coexistence of two or more autoimmune endocrine diseases is pathognomonic for autoimmune polyglandular syndrome. Autoimmune thyroiditis and type 1 diabetes mellitus are the most common combination of autoimmune endocrine diseases reported. Most studies reported the prevalence of autoimmune thyroiditis in "typical" type 1 adult diabetic subjects about 20 - 40%. Little is known about the prevalence of autoimmune thyroiditis in subjects with LADA. Only a few studies confirmed a high prevalence of thyroid autoantibodies in type 2 diabetic subjects with GADA compared to type 2 diabetic subjects without GADA and compared to non-diabetic population too.

Authors+Show Affiliations

Institute of Endocrinology, 11694 Prague, Czech Republic. mbehanova@endo.cz

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

11674844

Citation

Matejkova-Behanova, M. "Latent Autoimmune Diabetes in Adults (LADA) and Autoimmune Thyroiditis." Endocrine Regulations, vol. 35, no. 3, 2001, pp. 167-72.
Matejkova-Behanova M. Latent autoimmune diabetes in adults (LADA) and autoimmune thyroiditis. Endocr Regul. 2001;35(3):167-72.
Matejkova-Behanova, M. (2001). Latent autoimmune diabetes in adults (LADA) and autoimmune thyroiditis. Endocrine Regulations, 35(3), pp. 167-72.
Matejkova-Behanova M. Latent Autoimmune Diabetes in Adults (LADA) and Autoimmune Thyroiditis. Endocr Regul. 2001;35(3):167-72. PubMed PMID: 11674844.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Latent autoimmune diabetes in adults (LADA) and autoimmune thyroiditis. A1 - Matejkova-Behanova,M, PY - 2001/10/25/pubmed PY - 2002/1/5/medline PY - 2001/10/25/entrez SP - 167 EP - 72 JF - Endocrine regulations JO - Endocr Regul VL - 35 IS - 3 N2 - Latent autoimmune diabetes in adults (LADA) is characterized by clinical presentation as type 2 diabetes after 25 years of age, initial control achieved with diet or oral hypoglycaemic agents during at least 6 months, presence of autoantibodies (first of all GADA) and some immunogenetic features of diabetes mellitus type 1. In patients with an autoimmune endocrine disease, which could be also autoimmune diabetes, there is a high risk of development of another autoimmune endocrine disorder. The coexistence of two or more autoimmune endocrine diseases is pathognomonic for autoimmune polyglandular syndrome. Autoimmune thyroiditis and type 1 diabetes mellitus are the most common combination of autoimmune endocrine diseases reported. Most studies reported the prevalence of autoimmune thyroiditis in "typical" type 1 adult diabetic subjects about 20 - 40%. Little is known about the prevalence of autoimmune thyroiditis in subjects with LADA. Only a few studies confirmed a high prevalence of thyroid autoantibodies in type 2 diabetic subjects with GADA compared to type 2 diabetic subjects without GADA and compared to non-diabetic population too. SN - 1210-0668 UR - https://www.unboundmedicine.com/medline/citation/11674844/Latent_autoimmune_diabetes_in_adults__LADA__and_autoimmune_thyroiditis_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -