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Chronic idiopathic urticaria treatment.
Allergol Immunopathol (Madr). 2001 Jul-Aug; 29(4):129-32.AI

Abstract

Chronic idiopathic urticaria (CIU) is a common skin condition that affects 0.1-3 % of people in the USA and Europe and accounts for nearly 75 % of all chronic urticaria cases. Up to 40 % of patients who have chronic urticaria for more than 6 months still have urticarial wheals 10 years later. The therapeutic management should first be oriented towards palliation of symptoms. A 2 % solution of ephedrine as a local spray is very useful for oropharyngeal edema. H1 antihistamines with a low potential for sedation are the most important first-line treatment. Combinations of various antihistamines may be useful in suppressing symptomatology. These include: a) First generation H1 antihistamines; b) Combinations of first and second generations using non-sedating agents in the morning and first generation drugs at night; c) Combinations of second generation antihistamines; d) Combination of doxepin with a first or second generation antihistamine; e) Combination of an H2 anti-receptor antihistamine (eg, cimetidine or ranitidine) with a first or second generation antihistamine. Preliminary reports suggest that desloratadine and anti-leukotrienes may be effective in treating some patients with chronic idiopathic urticaria.

Authors+Show Affiliations

Allergy Section. "Virgen de la Arrixaca" University Hospital. Associated Professor of Allergy. University of Murcia. Murcia. Spain. jnegroa@meditex.esNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11674926

Citation

Negro-Alvarez, J M., and J C. Miralles-López. "Chronic Idiopathic Urticaria Treatment." Allergologia Et Immunopathologia, vol. 29, no. 4, 2001, pp. 129-32.
Negro-Alvarez JM, Miralles-López JC. Chronic idiopathic urticaria treatment. Allergol Immunopathol (Madr). 2001;29(4):129-32.
Negro-Alvarez, J. M., & Miralles-López, J. C. (2001). Chronic idiopathic urticaria treatment. Allergologia Et Immunopathologia, 29(4), 129-32.
Negro-Alvarez JM, Miralles-López JC. Chronic Idiopathic Urticaria Treatment. Allergol Immunopathol (Madr). 2001 Jul-Aug;29(4):129-32. PubMed PMID: 11674926.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chronic idiopathic urticaria treatment. AU - Negro-Alvarez,J M, AU - Miralles-López,J C, PY - 2001/10/25/pubmed PY - 2002/1/5/medline PY - 2001/10/25/entrez SP - 129 EP - 32 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 29 IS - 4 N2 - Chronic idiopathic urticaria (CIU) is a common skin condition that affects 0.1-3 % of people in the USA and Europe and accounts for nearly 75 % of all chronic urticaria cases. Up to 40 % of patients who have chronic urticaria for more than 6 months still have urticarial wheals 10 years later. The therapeutic management should first be oriented towards palliation of symptoms. A 2 % solution of ephedrine as a local spray is very useful for oropharyngeal edema. H1 antihistamines with a low potential for sedation are the most important first-line treatment. Combinations of various antihistamines may be useful in suppressing symptomatology. These include: a) First generation H1 antihistamines; b) Combinations of first and second generations using non-sedating agents in the morning and first generation drugs at night; c) Combinations of second generation antihistamines; d) Combination of doxepin with a first or second generation antihistamine; e) Combination of an H2 anti-receptor antihistamine (eg, cimetidine or ranitidine) with a first or second generation antihistamine. Preliminary reports suggest that desloratadine and anti-leukotrienes may be effective in treating some patients with chronic idiopathic urticaria. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/11674926/Chronic_idiopathic_urticaria_treatment_ L2 - http://www.elsevier.es/en/linksolver/ft/ivp/0301-0546/29/129 DB - PRIME DP - Unbound Medicine ER -