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[Genetic aspects of colorectal cancer].
Rev Med Brux. 2001 Sep; 22(4):A199-202.RM

Abstract

Cancer is a hereditary disease at the level of an individual cell and its daughter cells. The tumor genotype causing the tumor phenotype is now quite well known in colorectal cancer and allows, among others, to perform pathology examination at the molecular level. A distinct topic addresses individual predisposition to colorectal cancer. Its molecular nature is well know in the relatively rare cases, about 5-10% of colorectal cancers, where such a predisposition is major, and is transmitted in families of affected subjects following a hereditary, mendelian mode of inheritance. Specifically, two types of hereditary adenomatous tumors, polyposis and hereditary nonpolyposis colorectal cancer, may benefit from genetic analysis in order to target cancer prevention. New genetic tests will probably develop in the coming years, allowing for the analysis of more modest, and less clearly hereditary individual risks.

Authors+Show Affiliations

Service de Génétique Médicale, Centre de Génétique, Laboratoire de Génétique Médicale, Hôpital Erasme, U.L.B.

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

fre

PubMed ID

11680173

Citation

Abramowicz, M. "[Genetic Aspects of Colorectal Cancer]." Revue Medicale De Bruxelles, vol. 22, no. 4, 2001, pp. A199-202.
Abramowicz M. [Genetic aspects of colorectal cancer]. Rev Med Brux. 2001;22(4):A199-202.
Abramowicz, M. (2001). [Genetic aspects of colorectal cancer]. Revue Medicale De Bruxelles, 22(4), A199-202.
Abramowicz M. [Genetic Aspects of Colorectal Cancer]. Rev Med Brux. 2001;22(4):A199-202. PubMed PMID: 11680173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Genetic aspects of colorectal cancer]. A1 - Abramowicz,M, PY - 2001/10/30/pubmed PY - 2002/1/5/medline PY - 2001/10/30/entrez SP - A199 EP - 202 JF - Revue medicale de Bruxelles JO - Rev Med Brux VL - 22 IS - 4 N2 - Cancer is a hereditary disease at the level of an individual cell and its daughter cells. The tumor genotype causing the tumor phenotype is now quite well known in colorectal cancer and allows, among others, to perform pathology examination at the molecular level. A distinct topic addresses individual predisposition to colorectal cancer. Its molecular nature is well know in the relatively rare cases, about 5-10% of colorectal cancers, where such a predisposition is major, and is transmitted in families of affected subjects following a hereditary, mendelian mode of inheritance. Specifically, two types of hereditary adenomatous tumors, polyposis and hereditary nonpolyposis colorectal cancer, may benefit from genetic analysis in order to target cancer prevention. New genetic tests will probably develop in the coming years, allowing for the analysis of more modest, and less clearly hereditary individual risks. SN - 0035-3639 UR - https://www.unboundmedicine.com/medline/citation/11680173/[Genetic_aspects_of_colorectal_cancer]_ L2 - http://www.diseaseinfosearch.org/result/1746 DB - PRIME DP - Unbound Medicine ER -