Tags

Type your tag names separated by a space and hit enter

Dyspepsia and gastric emptying in chronic renal failure patients.
Clin Nephrol. 2001 Oct; 56(4):302-7.CN

Abstract

AIMS

Chronic renal failure (CRF) patients frequently suffer from dyspeptic complaints such as nausea, vomiting, abdominal distension, early satiety and anorexia. The aim of the present study was to define the prevalence of dyspeptic complaints and delayed gastric emptying in CRF patients.

MATERIAL AND METHODS

Dyspeptic complaints were assessed anamnestically in 62 non-dialyzed CRF patients. Gastric emptying for solids was evaluated by the 13C-octanoic acid breath test in the same population. The CRF patients were compared to 27 healthy volunteers.

RESULTS

There was a high prevalence (48%) of dysmotility-like dyspepsia in the investigated population. The gastric emptying rates of CRF patients and healthy volunteers were significantly different (median gastric emptying t(1/2) 83 min versus 60 min, p < 0.01). Diabetic CRF patients had lower gastric emptying rates than non-diabetic CRF patients (median gastric emptying time t(1/2) 113 min versus 77 min, p < 0.01). Even the non-diabetic CRF patients had a significantly delayed gastric emptying rate compared to the healthy volunteers (77 min versus 60 min, p < 0.05).

CONCLUSION

It is concluded that dysmotility-like dyspeptic complaints and delayed gastric emptying are highly prevalent in CRF patients.

Authors+Show Affiliations

Department of Internal Medicine, Ghent University Hospital, Belgium. bruno.vanvlem@rug.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11680660

Citation

Van Vlem, B, et al. "Dyspepsia and Gastric Emptying in Chronic Renal Failure Patients." Clinical Nephrology, vol. 56, no. 4, 2001, pp. 302-7.
Van Vlem B, Schoonjans R, Vanholder R, et al. Dyspepsia and gastric emptying in chronic renal failure patients. Clin Nephrol. 2001;56(4):302-7.
Van Vlem, B., Schoonjans, R., Vanholder, R., Vandamme, W., De Vos, M., & Lameire, N. (2001). Dyspepsia and gastric emptying in chronic renal failure patients. Clinical Nephrology, 56(4), 302-7.
Van Vlem B, et al. Dyspepsia and Gastric Emptying in Chronic Renal Failure Patients. Clin Nephrol. 2001;56(4):302-7. PubMed PMID: 11680660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dyspepsia and gastric emptying in chronic renal failure patients. AU - Van Vlem,B, AU - Schoonjans,R, AU - Vanholder,R, AU - Vandamme,W, AU - De Vos,M, AU - Lameire,N, PY - 2001/10/30/pubmed PY - 2002/2/22/medline PY - 2001/10/30/entrez SP - 302 EP - 7 JF - Clinical nephrology JO - Clin Nephrol VL - 56 IS - 4 N2 - AIMS: Chronic renal failure (CRF) patients frequently suffer from dyspeptic complaints such as nausea, vomiting, abdominal distension, early satiety and anorexia. The aim of the present study was to define the prevalence of dyspeptic complaints and delayed gastric emptying in CRF patients. MATERIAL AND METHODS: Dyspeptic complaints were assessed anamnestically in 62 non-dialyzed CRF patients. Gastric emptying for solids was evaluated by the 13C-octanoic acid breath test in the same population. The CRF patients were compared to 27 healthy volunteers. RESULTS: There was a high prevalence (48%) of dysmotility-like dyspepsia in the investigated population. The gastric emptying rates of CRF patients and healthy volunteers were significantly different (median gastric emptying t(1/2) 83 min versus 60 min, p < 0.01). Diabetic CRF patients had lower gastric emptying rates than non-diabetic CRF patients (median gastric emptying time t(1/2) 113 min versus 77 min, p < 0.01). Even the non-diabetic CRF patients had a significantly delayed gastric emptying rate compared to the healthy volunteers (77 min versus 60 min, p < 0.05). CONCLUSION: It is concluded that dysmotility-like dyspeptic complaints and delayed gastric emptying are highly prevalent in CRF patients. SN - 0301-0430 UR - https://www.unboundmedicine.com/medline/citation/11680660/Dyspepsia_and_gastric_emptying_in_chronic_renal_failure_patients_ L2 - https://www.diseaseinfosearch.org/result/2394 DB - PRIME DP - Unbound Medicine ER -