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Dietary salt alters pulmonary function during exercise in exercise-induced asthmatics.
J Sports Sci 2001; 19(11):865-73JS

Abstract

Epidemiological and experimental studies have suggested that dietary salt may play a role in airway responsiveness. We have previously shown that a low salt diet improves and a high salt diet exacerbates post-exercise pulmonary function in individuals with exercise-induced asthma. The aim of this study was to determine the influence of both elevated and restricted salt diets on pulmonary function during exercise in individuals with exercise-induced asthma. Nine men and six women participated in this double-blind, crossover study. The participants entered the study on their normal salt diet and were placed on either a low or high salt diet for 2 weeks. Each diet was randomized, with a 1 week washout period between diets before crossing over to the alternative diet for 2 weeks. The participants underwent treadmill testing at 85% of their age-predicted heart rate on the normal salt diet and at the end of each treatment period. Pulmonary function was assessed during exercise by arterial saturation (ear oximetry) and indirect calorimetry. Twenty-four hour urine collections confirmed compliance with the diets. Arterial saturation was reduced on the high and improved on the low salt diet at higher exercise intensities. Tidal volume and frequency selection during exercise varied with the diets, with a higher tidal volume and lower frequency on the high salt diet, but a lower tidal volume and higher frequency on the low salt diet. This suggested greater airway resistance during the high salt diet. In conclusion, the low salt diet improved and the high salt diet exacerbated pulmonary function during exercise in individuals with exercise-induced asthma. The mechanism of action remains unclear.

Authors+Show Affiliations

School of Sport Science, Physical Education and Recreation, University of Wales Institute, Cardiff, UK. tmickleborough@uwic.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

11695508

Citation

Mickleborough, T D., et al. "Dietary Salt Alters Pulmonary Function During Exercise in Exercise-induced Asthmatics." Journal of Sports Sciences, vol. 19, no. 11, 2001, pp. 865-73.
Mickleborough TD, Gotshall RW, Cordain L, et al. Dietary salt alters pulmonary function during exercise in exercise-induced asthmatics. J Sports Sci. 2001;19(11):865-73.
Mickleborough, T. D., Gotshall, R. W., Cordain, L., & Lindley, M. (2001). Dietary salt alters pulmonary function during exercise in exercise-induced asthmatics. Journal of Sports Sciences, 19(11), pp. 865-73.
Mickleborough TD, et al. Dietary Salt Alters Pulmonary Function During Exercise in Exercise-induced Asthmatics. J Sports Sci. 2001;19(11):865-73. PubMed PMID: 11695508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary salt alters pulmonary function during exercise in exercise-induced asthmatics. AU - Mickleborough,T D, AU - Gotshall,R W, AU - Cordain,L, AU - Lindley,M, PY - 2001/11/7/pubmed PY - 2002/3/1/medline PY - 2001/11/7/entrez SP - 865 EP - 73 JF - Journal of sports sciences JO - J Sports Sci VL - 19 IS - 11 N2 - Epidemiological and experimental studies have suggested that dietary salt may play a role in airway responsiveness. We have previously shown that a low salt diet improves and a high salt diet exacerbates post-exercise pulmonary function in individuals with exercise-induced asthma. The aim of this study was to determine the influence of both elevated and restricted salt diets on pulmonary function during exercise in individuals with exercise-induced asthma. Nine men and six women participated in this double-blind, crossover study. The participants entered the study on their normal salt diet and were placed on either a low or high salt diet for 2 weeks. Each diet was randomized, with a 1 week washout period between diets before crossing over to the alternative diet for 2 weeks. The participants underwent treadmill testing at 85% of their age-predicted heart rate on the normal salt diet and at the end of each treatment period. Pulmonary function was assessed during exercise by arterial saturation (ear oximetry) and indirect calorimetry. Twenty-four hour urine collections confirmed compliance with the diets. Arterial saturation was reduced on the high and improved on the low salt diet at higher exercise intensities. Tidal volume and frequency selection during exercise varied with the diets, with a higher tidal volume and lower frequency on the high salt diet, but a lower tidal volume and higher frequency on the low salt diet. This suggested greater airway resistance during the high salt diet. In conclusion, the low salt diet improved and the high salt diet exacerbated pulmonary function during exercise in individuals with exercise-induced asthma. The mechanism of action remains unclear. SN - 0264-0414 UR - https://www.unboundmedicine.com/medline/citation/11695508/Dietary_salt_alters_pulmonary_function_during_exercise_in_exercise_induced_asthmatics_ L2 - http://www.tandfonline.com/doi/full/10.1080/026404101753113813 DB - PRIME DP - Unbound Medicine ER -