Tags

Type your tag names separated by a space and hit enter

Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction.
J Periodontol. 2001 Oct; 72(10):1354-63.JP

Abstract

BACKGROUND

The aim of the present study was to identify Treponema socranskii in addition to Treponema denticola and Porphyromonas gingivalis by polymerase chain reaction (PCR), and to clarify the relationship between the presence of these microorganisms and the severity of clinical periodontal parameters.

METHODS

Saliva and subgingival plaque collected from 123 subjects (38 aggressive periodontitis patients, 65 chronic periodontitis patients, 20 healthy patients) were subjected to PCR to detect the aforementioned 3 microorganisms.

RESULTS

Detection frequencies of T. socranskii, T. denticola, and P. gingivalis in plaque samples from aggressive periodontitis patients (71.1%, 73.7%, 84.2%, respectively) and chronic periodontitis patients (89.2%, 93.8%, 95.3%) were much higher than those from healthy subjects (30%, 5.0%, 10.0%). In aggressive and chronic periodontitis patients, these 3 species of bacteria were detected frequently at sites that showed deep periodontal pockets and severe attachment loss. The percentage of these bacteria-positive sites increased as the gingival index score of chronic periodontitis patients increased. T. socranskii was frequently detected together with T. denticola or P. gingivalis at the same sites, and coexistence of these microorganisms was frequently observed in deep periodontal pockets of aggressive periodontitis patients.

CONCLUSIONS

T. socranskii, T. denticola, and P. gingivalis were frequently detected in periodontitis patients by PCR. The prevalence of these 3 microorganisms was correlated with various clinical parameters. Taken together, our findings suggest that T. socranskii, T. denticola, and P. gingivalis are associated with the severity of periodontal tissue destruction.

Authors+Show Affiliations

Division of Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan. takeuchi.peri@tmd.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11699477

Citation

Takeuchi, Y, et al. "Treponema Socranskii, Treponema Denticola, and Porphyromonas Gingivalis Are Associated With Severity of Periodontal Tissue Destruction." Journal of Periodontology, vol. 72, no. 10, 2001, pp. 1354-63.
Takeuchi Y, Umeda M, Sakamoto M, et al. Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. J Periodontol. 2001;72(10):1354-63.
Takeuchi, Y., Umeda, M., Sakamoto, M., Benno, Y., Huang, Y., & Ishikawa, I. (2001). Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. Journal of Periodontology, 72(10), 1354-63.
Takeuchi Y, et al. Treponema Socranskii, Treponema Denticola, and Porphyromonas Gingivalis Are Associated With Severity of Periodontal Tissue Destruction. J Periodontol. 2001;72(10):1354-63. PubMed PMID: 11699477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. AU - Takeuchi,Y, AU - Umeda,M, AU - Sakamoto,M, AU - Benno,Y, AU - Huang,Y, AU - Ishikawa,I, PY - 2001/11/9/pubmed PY - 2002/1/17/medline PY - 2001/11/9/entrez SP - 1354 EP - 63 JF - Journal of periodontology JO - J. Periodontol. VL - 72 IS - 10 N2 - BACKGROUND: The aim of the present study was to identify Treponema socranskii in addition to Treponema denticola and Porphyromonas gingivalis by polymerase chain reaction (PCR), and to clarify the relationship between the presence of these microorganisms and the severity of clinical periodontal parameters. METHODS: Saliva and subgingival plaque collected from 123 subjects (38 aggressive periodontitis patients, 65 chronic periodontitis patients, 20 healthy patients) were subjected to PCR to detect the aforementioned 3 microorganisms. RESULTS: Detection frequencies of T. socranskii, T. denticola, and P. gingivalis in plaque samples from aggressive periodontitis patients (71.1%, 73.7%, 84.2%, respectively) and chronic periodontitis patients (89.2%, 93.8%, 95.3%) were much higher than those from healthy subjects (30%, 5.0%, 10.0%). In aggressive and chronic periodontitis patients, these 3 species of bacteria were detected frequently at sites that showed deep periodontal pockets and severe attachment loss. The percentage of these bacteria-positive sites increased as the gingival index score of chronic periodontitis patients increased. T. socranskii was frequently detected together with T. denticola or P. gingivalis at the same sites, and coexistence of these microorganisms was frequently observed in deep periodontal pockets of aggressive periodontitis patients. CONCLUSIONS: T. socranskii, T. denticola, and P. gingivalis were frequently detected in periodontitis patients by PCR. The prevalence of these 3 microorganisms was correlated with various clinical parameters. Taken together, our findings suggest that T. socranskii, T. denticola, and P. gingivalis are associated with the severity of periodontal tissue destruction. SN - 0022-3492 UR - https://www.unboundmedicine.com/medline/citation/11699477/Treponema_socranskii_Treponema_denticola_and_Porphyromonas_gingivalis_are_associated_with_severity_of_periodontal_tissue_destruction_ L2 - https://doi.org/10.1902/jop.2001.72.10.1354 DB - PRIME DP - Unbound Medicine ER -