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Preventive strategies in chronic liver disease: part I. Alcohol, vaccines, toxic medications and supplements, diet and exercise.

Abstract

Chronic liver disease is the 10th leading cause of death in the United States. Hepatitis C virus infection is the most frequent cause of chronic liver disease and the most common indication for liver transplantation. Preventive care can significantly reduce the progression of liver disease. Alcohol and hepatitis C virus are synergistic in hastening the development of cirrhosis; therefore, patients with hepatitis C infection should abstain from alcohol use. Because superinfection with hepatitis A or B virus can lead to liver failure, vaccination is recommended. Potentially hepatotoxic medications should be used with caution in patients with chronic liver disease. In general, nonsteroidal anti-inflammatory drugs should be avoided; acetaminophen in a dosage below 2 g per day is the safest choice. Many herbal remedies are potentially hepatotoxic, and only milk thistle can be used safely in patients who have chronic liver disease. Weight reduction and exercise can improve liver function in patients with fatty liver.

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  • Authors+Show Affiliations

    ,

    Pennsylvania State University College of Medicine, Hershey, USA. triley@psu.edu

    Source

    American family physician 64:9 2001 Nov 01 pg 1555-60

    MeSH

    Alcohol Drinking
    Anti-Inflammatory Agents, Non-Steroidal
    Chemical and Drug Induced Liver Injury
    Chronic Disease
    Diet
    Exercise
    Family Practice
    Hepatitis C
    Humans
    Liver Diseases

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    11730310

    Citation

    Riley, T R., and A M. Bhatti. "Preventive Strategies in Chronic Liver Disease: Part I. Alcohol, Vaccines, Toxic Medications and Supplements, Diet and Exercise." American Family Physician, vol. 64, no. 9, 2001, pp. 1555-60.
    Riley TR, Bhatti AM. Preventive strategies in chronic liver disease: part I. Alcohol, vaccines, toxic medications and supplements, diet and exercise. Am Fam Physician. 2001;64(9):1555-60.
    Riley, T. R., & Bhatti, A. M. (2001). Preventive strategies in chronic liver disease: part I. Alcohol, vaccines, toxic medications and supplements, diet and exercise. American Family Physician, 64(9), pp. 1555-60.
    Riley TR, Bhatti AM. Preventive Strategies in Chronic Liver Disease: Part I. Alcohol, Vaccines, Toxic Medications and Supplements, Diet and Exercise. Am Fam Physician. 2001 Nov 1;64(9):1555-60. PubMed PMID: 11730310.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Preventive strategies in chronic liver disease: part I. Alcohol, vaccines, toxic medications and supplements, diet and exercise. AU - Riley,T R,3rd AU - Bhatti,A M, PY - 2001/12/4/pubmed PY - 2002/1/5/medline PY - 2001/12/4/entrez SP - 1555 EP - 60 JF - American family physician JO - Am Fam Physician VL - 64 IS - 9 N2 - Chronic liver disease is the 10th leading cause of death in the United States. Hepatitis C virus infection is the most frequent cause of chronic liver disease and the most common indication for liver transplantation. Preventive care can significantly reduce the progression of liver disease. Alcohol and hepatitis C virus are synergistic in hastening the development of cirrhosis; therefore, patients with hepatitis C infection should abstain from alcohol use. Because superinfection with hepatitis A or B virus can lead to liver failure, vaccination is recommended. Potentially hepatotoxic medications should be used with caution in patients with chronic liver disease. In general, nonsteroidal anti-inflammatory drugs should be avoided; acetaminophen in a dosage below 2 g per day is the safest choice. Many herbal remedies are potentially hepatotoxic, and only milk thistle can be used safely in patients who have chronic liver disease. Weight reduction and exercise can improve liver function in patients with fatty liver. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/11730310/full_citation L2 - http://www.aafp.org/link_out?pmid=11730310 DB - PRIME DP - Unbound Medicine ER -