Tags

Type your tag names separated by a space and hit enter

Detection of perfluorocarbons in blood by headspace solid-phase microextraction combined with gas chromatography/mass spectrometry.
Biomed Chromatogr. 2001 Nov; 15(7):443-51.BC

Abstract

A new method of detection of perfluorocarbon molecules (PFCs) in blood sample has been established. After an extraction and pre-concentration step performed by headspace solid-phase microextraction (HS-SPME), the PFCs are detected by gas chromatography-mass spectrometry (GC/MS) with an ion trap mass spectrometer in MS and MS/MS modes. The influence of different parameters on the SPME process is discussed. The limit of detection and the linearity of the procedure have been determined for two PFCs.

Authors+Show Affiliations

Mathurin JC
Laboratoire National de Dépistage du Dopage, Châtenay Malabry, France. jc.mathurin@wanadoo.fr
de Ceaurriz J
No affiliation info available
Audran M
No affiliation info available
Krafft MP
No affiliation info available

MeSH

FluorocarbonsGas Chromatography-Mass SpectrometryHumansQuality ControlSensitivity and SpecificityTemperature

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11746240

Citation

Mathurin, J C., et al. "Detection of Perfluorocarbons in Blood By Headspace Solid-phase Microextraction Combined With Gas Chromatography/mass Spectrometry." Biomedical Chromatography : BMC, vol. 15, no. 7, 2001, pp. 443-51.
Mathurin JC, de Ceaurriz J, Audran M, et al. Detection of perfluorocarbons in blood by headspace solid-phase microextraction combined with gas chromatography/mass spectrometry. Biomed Chromatogr. 2001;15(7):443-51.
Mathurin, J. C., de Ceaurriz, J., Audran, M., & Krafft, M. P. (2001). Detection of perfluorocarbons in blood by headspace solid-phase microextraction combined with gas chromatography/mass spectrometry. Biomedical Chromatography : BMC, 15(7), 443-51.
Mathurin JC, et al. Detection of Perfluorocarbons in Blood By Headspace Solid-phase Microextraction Combined With Gas Chromatography/mass Spectrometry. Biomed Chromatogr. 2001;15(7):443-51. PubMed PMID: 11746240.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection of perfluorocarbons in blood by headspace solid-phase microextraction combined with gas chromatography/mass spectrometry. AU - Mathurin,J C, AU - de Ceaurriz,J, AU - Audran,M, AU - Krafft,M P, PY - 2001/12/18/pubmed PY - 2002/2/1/medline PY - 2001/12/18/entrez SP - 443 EP - 51 JF - Biomedical chromatography : BMC JO - Biomed Chromatogr VL - 15 IS - 7 N2 - A new method of detection of perfluorocarbon molecules (PFCs) in blood sample has been established. After an extraction and pre-concentration step performed by headspace solid-phase microextraction (HS-SPME), the PFCs are detected by gas chromatography-mass spectrometry (GC/MS) with an ion trap mass spectrometer in MS and MS/MS modes. The influence of different parameters on the SPME process is discussed. The limit of detection and the linearity of the procedure have been determined for two PFCs. SN - 0269-3879 UR - https://www.unboundmedicine.com/medline/citation/11746240/Detection_of_perfluorocarbons_in_blood_by_headspace_solid_phase_microextraction_combined_with_gas_chromatography/mass_spectrometry_ L2 - https://doi.org/10.1002/bmc.79 DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓2]

Related Citations

More