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Sulfated polysaccharides from the red seaweed Georgiella confluens.
Carbohydr Res. 2002 Jan 07; 337(1):57-68.CR

Abstract

The water-soluble polysaccharides from Georgiella confluens, collected in Antarctica, were fractionated with cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration. The initially extracted polysaccharide and the major fraction isolated, soluble in 0.5 M NaCl, were studied. These are sulfated xylogalactans naturally rich in methylated sugar residues, comprising of 3,6-anhydro-2-O-methyl-L-galactose, 2-O-methyl-L-galactose and 6-O-methyl-D-galactose. Structural analysis was carried out by methylation, ethylation, desulfation-ethylation, desulfation-methylation, Smith degradation, 13C NMR spectroscopy and determination of the absolute configuration of monosaccharides by gas chromatography of diastereomeric derivatives produced by reductive amination. The results indicated the presence of an agaran backbone with an unusual substitution pattern: sulfation mainly at the 3-position of the alpha-L-galactose units and the presence of xylose side chains at the 4-position of the beta-D-galactose residues.

Authors+Show Affiliations

Departamento de Química Orgánica, CIHIDECAR-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11755912

Citation

Kolender, Adriana A., and María C. Matulewicz. "Sulfated Polysaccharides From the Red Seaweed Georgiella Confluens." Carbohydrate Research, vol. 337, no. 1, 2002, pp. 57-68.
Kolender AA, Matulewicz MC. Sulfated polysaccharides from the red seaweed Georgiella confluens. Carbohydr Res. 2002;337(1):57-68.
Kolender, A. A., & Matulewicz, M. C. (2002). Sulfated polysaccharides from the red seaweed Georgiella confluens. Carbohydrate Research, 337(1), 57-68.
Kolender AA, Matulewicz MC. Sulfated Polysaccharides From the Red Seaweed Georgiella Confluens. Carbohydr Res. 2002 Jan 7;337(1):57-68. PubMed PMID: 11755912.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sulfated polysaccharides from the red seaweed Georgiella confluens. AU - Kolender,Adriana A, AU - Matulewicz,María C, PY - 2002/1/5/pubmed PY - 2002/4/24/medline PY - 2002/1/5/entrez SP - 57 EP - 68 JF - Carbohydrate research JO - Carbohydr Res VL - 337 IS - 1 N2 - The water-soluble polysaccharides from Georgiella confluens, collected in Antarctica, were fractionated with cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration. The initially extracted polysaccharide and the major fraction isolated, soluble in 0.5 M NaCl, were studied. These are sulfated xylogalactans naturally rich in methylated sugar residues, comprising of 3,6-anhydro-2-O-methyl-L-galactose, 2-O-methyl-L-galactose and 6-O-methyl-D-galactose. Structural analysis was carried out by methylation, ethylation, desulfation-ethylation, desulfation-methylation, Smith degradation, 13C NMR spectroscopy and determination of the absolute configuration of monosaccharides by gas chromatography of diastereomeric derivatives produced by reductive amination. The results indicated the presence of an agaran backbone with an unusual substitution pattern: sulfation mainly at the 3-position of the alpha-L-galactose units and the presence of xylose side chains at the 4-position of the beta-D-galactose residues. SN - 0008-6215 UR - https://www.unboundmedicine.com/medline/citation/11755912/Sulfated_polysaccharides_from_the_red_seaweed_Georgiella_confluens_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S000862150100283X DB - PRIME DP - Unbound Medicine ER -