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Intraductal papillary-mucinous tumors of the pancreas: presentation of eight cases.
Wien Klin Wochenschr. 2001 Nov 15; 113(22):880-4.WK

Abstract

BACKGROUND AND STUDY AIMS

The mucinsecreting intraductal papillary-mucinous tumors of the pancreas are a rare entity with characteristic duodenoscopic and radiological features. These tumors have a broad spectrum of presentation. The diagnosis requires highly experienced and attentive endoscopists. Once diagnosed, resection of the tumor is recommended to prevent progression to malignancy. This surgical procedure has a low acceptance, mainly in the elderly patients. Therefore, a "wait and see" strategy may be necessary in those patients refusing operation.

PATIENTS AND METHODS

Between 1996 and 2000, intraductal papillary-mucinous tumors of the pancreas were diagnosed in eight patients (5 females, 3 males) using endoscopic retrograde cholangiopancreatography, and confirmed by brush cytology and/or histology and analyzed retrospectively.

RESULTS

The patients showed typical endoscopic and radiological findings: dilatation and mucin extrusion of the papillary orifice, easy passage of instruments into the dilated main pancreatic duct, which showed patchy filling defects after application of contrast medium. Patients were informed about the diagnosis in detail. Two patients were inoperable. Surgery was recommended to the other six patients. Two of the six patients agreed to surgical treatment. The remaining four patients were included in a follow-up protocol. These patients were observed for up to 5 years. Only one patient showed minor progression of ERCP-findings.

CONCLUSION

Intraductal papillary-mucinous tumors of the pancreas can be well characterized by means of endoscopy and radiology. Poor compliance to surgical treatment makes individual multidisciplinary management and follow-up necessary.

Authors+Show Affiliations

2nd Medical Department, General Hospital, Graz, Austria. Herbert.Wurzer@klinikum-graz.atNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11762126

Citation

Wurzer, H, et al. "Intraductal Papillary-mucinous Tumors of the Pancreas: Presentation of Eight Cases." Wiener Klinische Wochenschrift, vol. 113, no. 22, 2001, pp. 880-4.
Wurzer H, Brandstätter G, Worm HC, et al. Intraductal papillary-mucinous tumors of the pancreas: presentation of eight cases. Wien Klin Wochenschr. 2001;113(22):880-4.
Wurzer, H., Brandstätter, G., Worm, H. C., & Wolf, G. (2001). Intraductal papillary-mucinous tumors of the pancreas: presentation of eight cases. Wiener Klinische Wochenschrift, 113(22), 880-4.
Wurzer H, et al. Intraductal Papillary-mucinous Tumors of the Pancreas: Presentation of Eight Cases. Wien Klin Wochenschr. 2001 Nov 15;113(22):880-4. PubMed PMID: 11762126.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intraductal papillary-mucinous tumors of the pancreas: presentation of eight cases. AU - Wurzer,H, AU - Brandstätter,G, AU - Worm,H C, AU - Wolf,G, PY - 2002/1/5/pubmed PY - 2002/1/17/medline PY - 2002/1/5/entrez SP - 880 EP - 4 JF - Wiener klinische Wochenschrift JO - Wien Klin Wochenschr VL - 113 IS - 22 N2 - BACKGROUND AND STUDY AIMS: The mucinsecreting intraductal papillary-mucinous tumors of the pancreas are a rare entity with characteristic duodenoscopic and radiological features. These tumors have a broad spectrum of presentation. The diagnosis requires highly experienced and attentive endoscopists. Once diagnosed, resection of the tumor is recommended to prevent progression to malignancy. This surgical procedure has a low acceptance, mainly in the elderly patients. Therefore, a "wait and see" strategy may be necessary in those patients refusing operation. PATIENTS AND METHODS: Between 1996 and 2000, intraductal papillary-mucinous tumors of the pancreas were diagnosed in eight patients (5 females, 3 males) using endoscopic retrograde cholangiopancreatography, and confirmed by brush cytology and/or histology and analyzed retrospectively. RESULTS: The patients showed typical endoscopic and radiological findings: dilatation and mucin extrusion of the papillary orifice, easy passage of instruments into the dilated main pancreatic duct, which showed patchy filling defects after application of contrast medium. Patients were informed about the diagnosis in detail. Two patients were inoperable. Surgery was recommended to the other six patients. Two of the six patients agreed to surgical treatment. The remaining four patients were included in a follow-up protocol. These patients were observed for up to 5 years. Only one patient showed minor progression of ERCP-findings. CONCLUSION: Intraductal papillary-mucinous tumors of the pancreas can be well characterized by means of endoscopy and radiology. Poor compliance to surgical treatment makes individual multidisciplinary management and follow-up necessary. SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/11762126/Intraductal_papillary_mucinous_tumors_of_the_pancreas:_presentation_of_eight_cases_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -